Sökning: "cell-free hemoglobin"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden cell-free hemoglobin.

  1. 1. Preterm intraventricular cerebral hemorrhage: role of cell-free hemoglobin

    Författare :Alex Adusei Agyemang; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intraventricular hemorrhage; Preterm birth; Haptoglobin; Alpha 1 microglobulin; cerebellar hypoplasia; periventricular white matter; cell-free hemoglobin;

    Sammanfattning : Cerebral intraventricular hemorrhage in preterm infants continues to be a major clinical problem associated with neurodevelopmental abnormalities manifested by cognitive, behavioral, attentional, social and motor deficits. Hypothesis and aims: The central thesis is that the cytotoxicity of extravasated blood and of consequently released cell-free hemoglobin(Hb) is pivotal for the pathophysiological events causally involved in brain injury. LÄS MER

  3. 2. Towards New Generation of Hemoglobin-Based Blood Substitutes

    Författare :Sandeep Chakane; Tillämpad biokemi; []
    Nyckelord :hemoglobin; Fetal hemoglobin; Hemoglobin-based oxygen carrier; DNA cleavage; comet assay;

    Sammanfattning : Blood transfusion is a clinically significant and crucial process, which saves millions of lives every year. However,shortage of donated blood and the risk of virus transmission through transfusible blood seriously affect theavailability of the blood. LÄS MER

  4. 3. Cell-free hemoglobin, hyperoxemia and the immature brain during cardiopulmonary bypass circulation

    Författare :Åsa Jungner; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 4. Engineering of Human Fetal Hemoglobin

    Författare :Karin Kettisen; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fetal hemoglobin; protein engineering; recombinant protein production; protein purification; chromatography; oxygen carrier; redox reactions; net surface charge; DNA cleavage;

    Sammanfattning : In blood, the oxygen-transporting protein hemoglobin (Hb) governs the oxygenation of cells and tissues. Naturally, this protein has claimed a place in the center of the research field of artificial oxygen therapeutics. LÄS MER

  7. 5. Human Fetal Hemoglobin : Biochemical Characterization and Recombinant Production

    Författare :Khuanpiroon Ratanasopa; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Blood substitutes; HBOCs; HbF; recombinant hemoglobin; pseudoperoxidase; ITC; haptoglobin;

    Sammanfattning : Blood transfusion is a common medical procedure when oxygen supply in the body is impaired. However, blood transfusion is not always without risks. The uncontrolled spreading of blood borne pathogens such as HIV or hepatitis B and C virus has urged researchers to look for “blood substitutes”. LÄS MER