Sökning: "cell-cycle regulation"

Visar resultat 1 - 5 av 311 avhandlingar innehållade orden cell-cycle regulation.

  1. 1. The Polyamine Dependence of Cell Cycle Progression-Application in Breast Cancer Treatment

    Författare :Louise Myhre; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; tissue culture; histochemistry; Histology; cytochemistry; onkologi; cancer; Cytologi; oncology; cancerology; Cytology; cell cycle kinetics; cell cycle regulatory proteins; polyamine analogues; DENSPM; CGP48664; DFMO; cell cycle regulation; Polyamines; breast cancer; Djurfysiologi; Animal physiology; vävnadskultur; Histologi; cytokemi; histokemi;

    Sammanfattning : In the normal functioning organism, there is a balance between cell proliferation, cell differentiation, and cell death. An imbalance in these processes results in different diseases. This thesis concerns the imbalance where there is too little cell death and cell differentiation with increased cell proliferation. LÄS MER

  2. 2. Cell cycle regulation in cancer: A noncoding perspective

    Författare :Mohamad Ali; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long Noncoding RNA; lncRNA; Cell cycle; S phase; Mitosis; Checkpoint; Cancer; SCAT7; LY6K-AS;

    Sammanfattning : The cell cycle progression is tightly regulated to ensure error-free cell replication. The complexity of the transcriptional machinery aids to function in a spatiotemporal pattern across different phases and genomic loci. LÄS MER

  3. 3. Cell Cycle Regulation in Human Renal Cell Carcinoma

    Författare :Ylva Hedberg; Göran Landberg; Börje Ljungberg; Göran Roos; Ulf Bergerheim; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Human Renal Cell Carcinoma; Cell Cycle; G1 S; Protein; Cyclin; p27; pRb; Phosphorylation; Tissue Microarray; Clinical Behaviour; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : ABSTRACTCell cycle regulation in human renal cell carcinomaYlva Hedberg, Departments of Medical Biosciences, Pathology, and Surgical andPerioperative Sciences, Urology Andrology, Umeå University, SwedenDeregulated growth control is a hallmark of neoplasia potentially caused by aberrant expression of cell cycle regulatory proteins. The importance of such aberrations in human renal cell carcinoma (RCC) has not been fully clarified. LÄS MER

  4. 4. How precise is cyclic life? : Insights during a single molecule revolution of the bacterial cell cycle

    Författare :Mats Walldén; Johan Elf; Peter Graumann; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; E.coli; cell cycle; replication initiation; transcription factor; gene-regulation; single molecule microscopy; microfluidics; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Bacterial cells reproduce by doubling in size and dividing. The molecular control systems which regulate the cell cycle must do so in a manner which maintains a similar cell size over many generations. A cell can under conditions of fast growth conclude cell cycles in shorter time than the time required to replicate its chromosome. LÄS MER

  5. 5. Coping with Stress : Regulation of the Caulobacter crescentus cell cycle in response to environmental cues

    Författare :Kristina Heinrich; Kristina Jonas; Emanuele Biondi; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Caulobacter crescentus; bacteria; cell cycle; stress; filamentation; cell morphology; DNA replication; cell division; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : All organisms have to respond to environmental changes to maintain cellular and genome integrity. In particular, unicellular organisms like bacteria must be able to analyze their surroundings and rapidly adjust their growth mode and cell cycle program in response to environmental changes, such as changes in nutrient availability, temperature, osmolarity, or pH. LÄS MER