Sökning: "cell-cell interaction"

Visar resultat 6 - 10 av 49 avhandlingar innehållade orden cell-cell interaction.

  1. 6. Interactions between the stroma and thyroid epithelial cells of normal and malignant origin

    Författare :Thérèse Dahlman; Uppsala universitet; []
    Nyckelord :Medical sciences; Thyroid gland; carcinoma; collagen type I; EGF; TGF-b1; interaction; integrins; E-cadherin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Endocrine and locally produced factors as well as interactions between epithelial cells and the stroma important in the control of growth and function of the thyroid gland. In this study, the effects of, and mechanism(s) for, such cross-talk under some normal and pathological conditions were investigated. LÄS MER

  3. 7. Plasma membrane arabinogalactan proteins

    Författare :Lars Snogerup; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; arabinogalactan protein plant development cell-cell interaction plasma membrane; Plant biochemistry; Växtbiokemi;

    Sammanfattning : Arabinogalactan proteins (AGPs) are proteoglycans found at the outer side of the plasma membrane and in the extracellular matrix of plants. To be able to study the plasma membrane bound AGPs, a method using SDS-agarose gel electrophoresis (SDS-AGE) was developed to overcome the problems associated with electrophoretic separation of highly glycosylated proteins. LÄS MER

  4. 8. Platelet and leukocyte activation and their interaction : in experimental prothrombotic and inflammatory states

    Författare :Nailin Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerotic disease is associated with inflammation and thrombosis, both of which involve multi-cellular activation and interaction. The present work has investigated the mechanisms of platelet leukocyte cross-talk in vitro, and explored the possibility of multi-cellular activation in vivo in prothrombotic and inflammatory models in healthy volunteers. LÄS MER

  5. 9. Characterisation of integrin splice variants and the interaction between integrins and the urokinase receptor

    Författare :Gunbjørg Svineng; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; integrin β1; alternative splicing; Alu element; urokinase receptor; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Integrins are a family of receptors involved in adhesion to extracellular matrix proteins and in cell-cell contacts. Each integrin consists of one a and one β subunit. Our main interest has been the β1 subunit and its splice variants. LÄS MER

  7. 10. Deciphering Binding Patterns of Therapeutic Antibodies with Immune Cells : From Method Development to Application

    Författare :Sina Bondza; Jos Buijs; Marika Nestor; Mark Cragg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affinity; binding kinetics; CD20; cell-based assay; immunology; receptor-ligand interaction; therapeutic antibody; Immunologi; Immunology; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Reversible binding, for example between signaling molecules and receptors on the cell surface, is one of the main means to communicate information in cellular systems. Knowledge about how molecules interact is crucial for both understanding biological function and for therapeutic intervention. LÄS MER