Sökning: "cell surface mucin"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden cell surface mucin.

  1. 1. Mucus and mucins during gastrointestinal infections

    Författare :Nazanin Navabi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucin; gastrointestinal cell lines; mucus layer; secreted mucin; cell surface mucin; H. pylori; C. rodentium; ETEC; mucin secretion; goblet cells;

    Sammanfattning : The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate the changes in mucin and the mucus layer in the gastrointestinal tract during infection with the gastrointestinal pathogens C. LÄS MER

  3. 2. On the Development of Mucin-based Biomaterial Coatings

    Författare :Tomas Sandberg; Karin Caldwell; Jan Carlsson; Thomas Arnebrant; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucin; Biomaterial; Surface-exposed protein; XPS; Neutrophil; Cell morphology; SEM; QCM-D; Viscoelasticity; Protein-stabilization; HNL; Coating; MG1; BSM; PGM; SEC-MALS-RI; Mucin quantification; Protein adsorption; Ellipsometry; Biomaterials; Biomaterial;

    Sammanfattning : Owing to their key role in mucosal functioning as surface barriers with biospecific interaction potentials, the mucins are interesting candidates for use as surface modifiers in biomaterials applications. In this work, “mild” fractionation procedures were used to prepare mucins of bovine (BSM), porcine (PGM), and human (MG1) origin. LÄS MER

  4. 3. Glycan dependent Helicobacter spp. and Streptococcus oralis binding to mucins in the gastric and oral mucosal niches

    Författare :Gurdeep Chahal; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; Streptococcus; diversity; glycosylation;

    Sammanfattning : Helicobacter pylori infects the stomach of half of the world’s population, while Helicobacter suis colonizes pigs and is the most common non-H. pylori Helicobacter species that also infects human stomach. Infection with Helicobacter spp. is associated with chronic gastritis, peptic ulcer disease, and gastric cancer. LÄS MER

  5. 4. Helicobacter pylori Sialic Acid-Specific Surface Lectin

    Författare :Siiri Hirmo; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; mycology; Mikrobiologi; virology; bacteriology; haemagglutinin; Helicobacter pylori; sialic acid; sialidase; gastrointestinal mucin; milk glycoprotein; Microbiology; resonant mirror biosensor; virologi; mykologi;

    Sammanfattning : Helicobacter pylori is a gastric pathogen colonising the gastric mucus layer and epithelium of gastric tissue and is associated with chronic type B gastritis and peptic ulcer disease. The attachment of H. pylori to gastric epithelial cells involves several structures recognised by specific bacterial surface proteins. LÄS MER

  7. 5. The Relationship between Transmembrane Mucins, Ion Channels and PDZ Adaptor Proteins in the Small Intestine

    Författare :Thaher Pelaseyed; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucin; MUC3; MUC17; SEA; PDZK1; GOPC; CFTR; NHE3;

    Sammanfattning : The human body is continuously exposed to challenges from the surrounding world. In analogy with the skin, mucus is a well-organized and highly regulated barrier composed of polymeric and O-glycosylated mucins that protects luminal organs such as the gastrointestinal tracts from the outer milieu. LÄS MER