Sökning: "cell sorting"

Visar resultat 6 - 10 av 139 avhandlingar innehållade orden cell sorting.

1. 6. Miniaturised Microwell-based Cell Assays

   Författare :Emilie Weibull; Helene Andersson Svahn; Albert van den Berg; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microwell; miniaturisation; high-resolution imaging; high-throughput; cell culture; single-cell; clone; heterogeneity; antibiotic susceptibility testing; concentration gradient; interfacing; microchannels; cell retrieval;

   Sammanfattning : Cell heterogeneity in genetically identical cell populations is becoming a well-known and important phenomenon in cell biology. Current methods commonly utilise population-based analysis founded on averaged result. Hence there is a need for high-throughput cell assays on the single-cell level. LÄS MER

3. 7. Histone H1 : Subtypes and phosphorylation in cell life and death

   Författare :Anna Gréen; Ingemar Rundquist; Peter Söderkvist; Rolf Ohlsson; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Cellbiologi;

   Sammanfattning : The genetic information of a human diploid cell is contained within approximately 2 metres of linear DNA. The DNA molecules are compacted and organized in various ways to fit inside the cell nucleus. Various kinds of histones are involved in this compaction. One of these histones, histone H1 is the topic of the present thesis. LÄS MER

4. 8. T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway

   Författare :Susann Karlsson; Carina Hellberg; Carl-Henrik Heldin; Bengt Hallberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; TC-PTP; receptor trafficking; PK-M2; Medical cell biology; Medicinsk cellbiologi; molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : Platelet-derived growth factor (PDGF) is a potent stimulator of cell growth, survival and motility. PDGF exerts its function by binding to specific tyrosine kinase receptors, initiating receptor auotphosphorylation and initiation of specific signaling pathways that regulates the cellular response. LÄS MER

5. 9. Microwell devices for single-cell analyses

   Författare :Sara Lindström; Helene Andersson-Svahn; Mehmet Toner; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microwell; miniaturization; microfluidics; cell culture; single-cell; clone; imaging; stem cell; cancer; low volume; high-throughput; Molecular biology; Molekylärbiologi;

   Sammanfattning : Powerful tools for detailed cellular studies are emerging, increasing the knowledge ofthe ultimate target of all drugs: the living cell. Today, cells are commonly analyzed inensembles, i.e. thousands of cells per sample, yielding results on the average responseof the cells. LÄS MER

7. 10. Ultrasonic Fluid and Cell Manipulation

   Författare :Mathias Ohlin; Martin Viklund; Hans Hertz; Peter Glynne-Jones; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 3D cell culture; Acoustic streaming; Acoustofluidics; Cell manipulation; High-resolution imaging; Multi-well; Microplate; Natural killer cell; Piezo; Radiation force; Solid tumor; Solubilization; Spheroid; Standing wave; Temperature control; Transducer; Trapping; Ultrasonic; Fysik; Physics; Biological Physics; Biologisk fysik;

   Sammanfattning : During the last decade, ultrasonic manipulation has matured into an important tool with a wide range of applications, from fundamental cell biological research to clinical and industrial implementations. The contactless nature of ultrasound makes it possible to manipulate living cells in a gentle way, e.g. LÄS MER