Sökning: "cell sorting"

Visar resultat 21 - 25 av 139 avhandlingar innehållade orden cell sorting.

1. 21. Identification and Characterization of Stem Cells in Preleukemia and Leukemia

   Författare :Lars Nilsson; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; extracellulära vätskor; Hematologi; Philadelphia chromosome; acute lymphoblastic leukemia; polycytemia vera; 5q- syndrome; myelodysplastic syndromes; self-renewal; preleukemia; Hematopoietic stem cells; leukemic stem cells; extracellular fluids;

   Sammanfattning : Hematopoietic stem cells (HSCs) are responsible for the daily and life long production of large numbers of mature blood cells through highly regulated self-renewal and multilineage capabilities. Leukemias on the other hand, are characterized by a clonal, dysregulated, lineage skewed proliferation and impaired differentiation as the result of multiple accumulated genetic events. LÄS MER

3. 22. Mucins, Cystic Fibrosis and PDZ protein interactions

   Författare :Emily Malmberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucin; PDZ; transmembrane; MUC1; Cystic Fibrosis; clathrin; CFTR; PDZK1; Bcr; endocytosis; MUC17;

   Sammanfattning : Cystic Fibrosis (CF) is caused and characterized by mutations in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. The dominating feature of the disease is mucus accumulation on mucosal surfaces, but no direct functional connection between mucus and CFTR is known. LÄS MER

4. 23. Non-canonical ATG8 conjugation in ESCRT-driven membrane remodeling processes

   Författare :Anastasia Knyazeva; Yao-Wen Wu; Richard Lundmark; Sascha Martens; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ATG8 conjugation; Endosomal Sorting Complex Required for Transport; membrane remodeling; chemical genetics;

   Sammanfattning : ATG8 family proteins have the unique ability to conjugate to membrane lipids. Initially identified as a hallmark of autophagy, ATG8 lipidation is emerging as an important regulator of a growing list of non-degradative cellular functions. LÄS MER

5. 24. Transcriptional Analysis of Cell-Sorted B-cell Lymphomas From High-throughput to Focused Identification of Molecular Targets

   Författare :Ulrika Andreasson; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microarray; molecular target; gene expression profiling; B-cell lymphoma; Fluorescence-activated cell sorting;

   Sammanfattning : B cell lymphomas (BCLs) are a group of severe cancers, afflicting both men and women at different ages. Gene expression profiling (GEP), have during the latest decades fundamentally contributed to a better classification and biological understanding of the different BCLs. LÄS MER

7. 25. Deterministic Lateral Displacement for Cell Separation

   Författare :Si Hoai Trung Tran; NanoLund: Centre for Nanoscience; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Deterministic lateral displacement; Cell Separation; Open microfluidics;

   Sammanfattning : In the fields of medicine and biology, the separation of particles is a central step in many preparative and analytical processes. Deterministic Lateral Displacement (DLD) has been a promising technique in the field of microfluidic particle and cell sorting, specifically for label-free separation with several applications of sorting by size, morphology, and deformation reported in the literature over the last decade. LÄS MER