Sökning: "cell polarity"

Visar resultat 6 - 10 av 73 avhandlingar innehållade orden cell polarity.

  1. 6. Cell-to-Cell Signalling in Arabidopsis Root Development

    Författare :Christina Joy Roberts; Annelie Carlsbecker; Dolf Weijers; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; HD-ZIP III; miRNA; plasmodesmata; auxin; ROS; xylem; Biologi med inriktning mot fysiologisk botanik; Biology with specialization in Physiological Botany;

    Sammanfattning : Development in multicellular organisms requires a strict balance between cell division and differentiation. The simple architecture of the Arabidopsis thaliana root makes it an ideal model for studying molecular mechanisms controlling both the transition from cell division to cell differentiation and cell fate determination. LÄS MER

  3. 7. Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

    Författare :Johan Heldin; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; cell migration; signaling; VEGF; FGD5; ExoC3L2; microRNA; RhoD; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Blood vessels deliver nutrients and oxygen to tissues. Importantly, the functions and growth of blood vessels are commonly altered in disease. The inside of all blood vessels are lined with endothelium, a thin specialized layer of endothelial cells that separate the blood from other tissues. LÄS MER

  4. 8. Cellular and molecular roles for CDC42 in angiogenesis

    Författare :Marco Castro; Christer Betsholtz; Bàrbara Laviña; Rui Benedito; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CDC42; angiogenesis; endothelial cell; vascular malformation; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Sammanfattning : Angiogenesis is the physiological process by which new blood vessels grow and critically depends on the interplay between the major vascular units: endothelial cells, pericytes and smooth muscle cells. Dysfunction and mispatterning of blood vessels are associated with the progression of many vascular complications, and therefore, understanding the causes of vascular dysmorphia is a central question in vascular biology. LÄS MER

  5. 9. The role of cell adhesion molecules in tissue formation and organogenesis

    Författare :Farzad Esni; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell adhesion cadherins N-CAM pancreas development mouse organogenesis;

    Sammanfattning : Cell adhesion molecules (CAMs) are cell surface glycoproteins that promote connection between two adjacent cells or between a cell and extra cellular matrix. These interactions are essential for tissue organisation during development and for the maintenance of tissue integrity in adult organisms. LÄS MER

  7. 10. Micro-environmental control of tumor differentiation and invasiveness

    Författare :Caroline Gélabert; Aristidis Moustakas; Alexander Pietras; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; cell signaling; TGFβ; non-coding RNAs; metabolism;

    Sammanfattning : The transforming growth factor β (TGFβ) family participates in embryonic development and adult tissue homeostasis. In early stages of tumorigenesis, TGFβ promotes cell cycle arrest and apoptosis; however, in advanced malignancies, TGFβ promotes tumor cell migration and metastasis via the induction of epithelial-tomesenchymal transition (EMT). LÄS MER