Sökning: "cell penetrating peptides"
Visar resultat 21 - 25 av 73 avhandlingar innehållade orden cell penetrating peptides.
21. Cell-penetrating peptides and oligonucleotide delivery
Sammanfattning : .... LÄS MER
22. Cell-penetrating peptides; chemical modification, mechanism of uptake and formulation development
Sammanfattning : Gene therapy holds the promise of revolutionizing the way we treat diseases. By using recombinant DNA and oligonucleotides (ONs), gene functions can be restored, altered or silenced according to the therapeutic need. LÄS MER
23. Cell-penetrating peptides in protein mimicry and oligonucleotide delivery : Applications and mechanisms
Sammanfattning : The plasma membrane functions as a barrier, restricting entry of hydrophilic pharmaceutical agents. Cell-penetrating peptides (CPPs) are capable of transporting bioactive cargos into the cell and have consequently been extensively investigated for their mechanism of entry and capability to deliver various cargos spanning from peptides to plasmids. LÄS MER
24. Rational modifications of cell-penetrating peptides for drug delivery : Applications in tumor targeting and oligonucleotide delivery
Sammanfattning : High molecular weight biomolecules are becoming important in the development of new therapeutics. However, their size and nature creates a major limitation for their application – poor penetration through biological membranes. LÄS MER
25. Cell-penetrating peptide based nanocomplexes for oligonucleotide delivery
Sammanfattning : Oligonucleotide-based drugs hold great promise for the treatment of many types of diseases, ranging from genetic disorders to viral infections and cancer. The problem is that efficient delivery across the cell membrane is required for oligonucleotides to have their desired effect. Cell-penetrating peptides (CPPs) provide a solution to this problem. LÄS MER