Sökning: "cell assemblies"

Visar resultat 1 - 5 av 45 avhandlingar innehållade orden cell assemblies.

  1. 1. Dynamics of Biomembranes and Rheological Properties of Living Cells

    Författare :Peter Berntsen; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell mechanics; lipid dynamics; cell rheology; biomembranes; water dynamics; relaxations; phospholipids; glass transition;

    Sammanfattning : An ingenious assembly of biomolecules and water constitute what we call biological tissue. The presence of water in this assembly is fundamental for the physiological processes and can make the difference between life and death. LÄS MER

  3. 2. Heparan Sulfate in the Amyloidosis and Inflammation of Alzheimer’s Disease

    Författare :Paul O'Callaghan; Xiao Zhang; Lars Lannfelt; Jeremy Turnbull; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; amyloidosis; amyloid-β; apolipoprotein E; astrocytes; glia; heparanase; heparan sulfate; heparan sulfate proteoglycans; microglia; neuroinflammation; Geriatrics; Geriatrik; Cellforskning; Cell Research; Neuroscience; Neurovetenskap; Pathology; Patologi;

    Sammanfattning : Alzheimer’s disease (AD) is a neurodegenerative disorder, with extensive evidence implicating the misfolding, aggregation and deposition of the amyloid-β (Aβ) peptide as central to the pathogenesis. Heparan sulfate (HS) is an interactive glycosaminoglycan, attached to core proteins as HS proteoglycans (HSPGs). LÄS MER

  4. 3. Islet amyloid polypeptide (IAPP) in Type 2 diabetes and Alzheimer disease

    Författare :Marie Oskarsson; Gunilla Westermark; Mikael Oliveberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; IAPP; Abeta; type 2 diabetes; Alzheimer disease; BRICHOS; heparan sulfate; islet amyloid; amyloid plaques; seeding; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : The misfolding and aggregation of the beta cell hormone islet amyloid polypeptide (IAPP) into amyloid fibrils is the main pathological finding in islets of Langerhans in type 2 diabetes. Pathological assemblies of IAPP are cytotoxic and believed to contribute to the loss of insulin-producing beta cells. LÄS MER

  5. 4. Development and characterization of functional composite materials for advanced energy conversion technologies

    Författare :Liangdong Fan; Bin Zhu; Torsten Fransson; Mahmut D. MAT; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Low temperature ceramic fuel cell; Ceria-carbonate composite; Electrolysis; Transition metal oxide; Symmetrical fuel cells; All-nanocomposite fuel cell; Electrolyte-free fuel cell; Solar cell; ion conductor and semiconductor; SRA - Energy; SRA - Energi;

    Sammanfattning : The solid oxide fuel cell (SOFC) is a potential high efficient electrochemical device for vehicles, auxiliary power units and large-scale stationary power plants combined heat and power application. The main challenges of this technology for market acceptance are associated with cost and lifetime due to the high temperature (700-1000 oC) operation and complex cell structure, i. LÄS MER

  7. 5. Investigations of neural attractor dynamics in human visual awareness

    Författare :David N. Silverstein; Pawel Herman; Martin Ingvar; Karl Friston; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; attractor dynamics; visual awareness; visual perception; visual attention; attentional blink; backward masking; gliomas; brain tumor; white matter; cell assemblies; neocortical model; threat response; fear signaling; amygdala; Biological Physics; Biologisk fysik; Computer Science; Datalogi; Tillämpad matematik och beräkningsmatematik; Applied and Computational Mathematics;

    Sammanfattning : What we see, how we see it and what emotions may arise from stimuli has long been studied by philosophers, psychologists, medical doctors and neuroscientists. This thesis work investigates a particular view on the possible dynamics, utilizing computational models of spiking neural attractor networks. LÄS MER