Sökning: "ceder"
Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet ceder.
1. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate
Sammanfattning : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. LÄS MER
2. Cancer biomarker discovery by in vitro systems biology
Sammanfattning : This Thesis was made with the intention to mechanistically assess and further develop a multi-stage cell line-based (in vitro) model for oral cancer development. Efforts of establishing additional tumor cell lines for expanding the model were coupled with the application of systems biology technologies for characterization of the three entities of the start-up model, including: 1) normal, 2) immortal and non-tumorigenic, versus 3) immortal and tumorigenic stages. LÄS MER
3. Cutting Through Water : Towards a Posthuman Theory of Educational Relationality
Sammanfattning : Based on an ongoing debate—academic as well as public—regarding the roles of the teacher and the student in education, this thesis explores educational relations within the field of philosophy of education. After critically examining intersubjective approaches to theories of educational relations, I localize anthropocentrism and subject-centrism (teacher/student) as two problematic aspects of the aforementioned approaches. LÄS MER
4. Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246
Sammanfattning : Tumor suppressor TP53 is the most frequently mutated gene in cancer. A majority of TP53 mutations result in a mutant p53 that disrupts its DNA binding capabilities but may also acquire novel gain-of-function activities that contribute to tumor growth. LÄS MER
5. Structure, evolution and expression of glandular kallikrein genes
Sammanfattning : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. LÄS MER