Sökning: "cbp3"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet cbp3.

  1. 1. Structure and Biogenesis of Membrane Proteins

    Författare :Mama Ndi; Martin Ott; Alexander Kastaniotis; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cbp3; cytochrome b; respiratory complex III; alternative translation initiation and sodium proton exchange; Biochemistry; biokemi;

    Sammanfattning : Membrane proteins make up about one-third of the cellular proteome. The diverse roles that membrane proteins have in cells include major life-sustaining processes, making them major drug targets. LÄS MER

  3. 2. Mechanistic Insights in the Biogenesis and Function of the Respiratory Chain

    Författare :Hannah Dawitz; Martin Ott; Cristina Ugalde; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; respiratory chain; bc1 complex; cytochrome c oxidase; Cbp3; Rcf1; Rcf2; respiratory supercomplexes; biogenesis; mitochondria; Saccharomyces cerevisiae; Biochemistry; biokemi;

    Sammanfattning : Mitochondria fulfill a plethora of functions, including harboring metabolic pathways and converting energy stored in metabolites into ATP, the common energy source of the cell. This last function is performed by the oxidative phosphorylation system, consisting of the respiratory chain and the ATP synthase. LÄS MER

  4. 3. Early steps in the biogenesis of the bc1 complex in yeast mitochondria : The role of the Cbp3-Cbp6 complex in cytochrome b synthesis and assembly

    Författare :Steffi Gruschke; Martin Ott; Dennis Winge; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; respiratory chain assembly; bc1 complex; mitochondrial gene expression; translational regulation; hemylation; Biochemistry; biokemi;

    Sammanfattning : The inner membrane of mitochondria harbors the complexes of the respiratory chain and the ATP synthase, which perform the key metabolic process oxidative phosphorylation. These complexes are composed of subunits from two different genetic origins: the majority of constituents is synthesized on cytosolic ribosomes and imported into mitochondria, but a handful of proteins, which represent core catalytic subunits, are encoded in the organellar DNA and translated on mitochondrial ribosomes. LÄS MER

  5. 4. Organization of mitochondrial gene expression in yeast : Specific features of organellar protein synthesis

    Författare :Kirsten Kehrein; Martin Ott; Thomas A Fox; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; translation; bc1 complex; ribosome; gene expression; Biochemistry; biokemi;

    Sammanfattning : Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. LÄS MER

  7. 5. The mitoribosome as a hub for integrating mitochondrial gene expression : Regulation of translation and early assembly of cytochrome b

    Författare :Andreas Carlström; Martin Ott; Chris Meisinger; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; gene expression; mitochondrial ribosome; translation regulation; feedback loop; biokemi; Biochemistry;

    Sammanfattning : The mitochondrial proteome is a mosaic of proteins from two different genetic systems. The majority of mitochondrial proteins are encoded in the nuclear genome and are synthesized in the cytosol before imported to mitochondria. LÄS MER