Sökning: "caveolin"
Visar resultat 16 - 20 av 38 avhandlingar innehållade ordet caveolin.
16. Insights into the role of spinal mTOR in the modulation of inflammation and nociception
Sammanfattning : Pain, especially chronic pain, is a major clinical problem. Pain therapy has proven to be complicated and the results are often unsatisfactory. Despite many years of research, the number of available pain therapeutics remains relatively small. LÄS MER
17. Caveolae structure and importance in insulin action
Sammanfattning : Type II diabetes is a disease characterized by chronic hyperglycaemia and abnormalities in lipid metabolism that affects approximately 5% of the population in the Western World. Caveolae are invaginations of the plasma membrane, described as 25-150 nm omega shaped structures, which are enriched in cholesterol, sphingolipids and the constituent protein caveolin. LÄS MER
18. Mechanisms of insulin signaling and the role of caveolae
Sammanfattning : Insulin regulates metabolic as well as mitogenic processes in target cells, involving a large number of mediators of signal transduction. In its role as a growth factor, insulin stimulates cell growth, in a process we demonstrate requires the participation of the Raf-1 kinase. LÄS MER
19. Expanding role of caveolae in control of adipocyte metabolism : proteomics of caveolae
Sammanfattning : The primary function of adipose tissue is to store energy in the form of triacylglycerol, which is hydrolyzed to fatty acids to supply other tissues with energy. While insulin promotes the storage of triacylglycerol, catecholamines stimulate its hydrolysis. LÄS MER
20. Extracellular matrix-mediated signaling in the regulation of vascular smooth muscle cell phenotype and function
Sammanfattning : Cardiovascular disease is the leading cause of mortality in the world. Even though death rates are today dropping in the developed countries, disability due to the disease is rising worldwide. The major portion of cardiovascular disease associated deaths is due to occlusive atherosclerotic lesions. LÄS MER