Sökning: "cathelicidin"

Visar resultat 6 - 10 av 28 avhandlingar innehållade ordet cathelicidin.

  1. 6. Studies of the role of the cathelicidin peptide LL-37 in epithelial biology

    Författare :Clara Ibel Chamorro Jimenez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The biology of epithelial immunity as well as of tissue repair is complex and highly regulated. A variety of molecules, cell types, and biological processes such as, cell differentiation, proliferation and migration, programmed cell death and antimicrobial mechanisms contribute to maintaining a balance between tissue damage and tissue repair. LÄS MER

  3. 7. Studies on Staphylococcus epidermidis biofilm formation and the bacterial interaction with the human cathelicidin antimicrobial peptide LL-37

    Författare :Eva Hell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The long-term use of central venous catheters for delivering nutrients and drugs in preterm neonates has been related to nosocomial infections. The majority of late-onset sepsis in very preterm infants (... LÄS MER

  4. 8. Urinary tract infection and renal scarring

    Författare :Milan Chromek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :urinary tract infection; renal scarring; cathelicidin; LL-3 7; NIMP-9; TIMP-1;

    Sammanfattning : Urinary tract infection (UTI) is the most common bacterial infection. Although most patients with UTI have a good prognosis, there is a risk of serious complications in a group of them. LÄS MER

  5. 9. Regulation of human cell viability by the host defence peptide LL-37

    Författare :Daniel Svensson; Kärlfysiologi; []
    Nyckelord :LL-37; cathelicidin; cytotoxicity; host defence peptides; autoimmune diseases; inflammation; vitamin D;

    Sammanfattning : Accumulating evidence suggests that the main human cathelicidin peptide, LL-37, may influence host cell viability and pro-inflammatory signaling when locally overexpressed. LL-37 has pro-inflammatory properties linked to the development of for example psoriasis, rosacea, SLE and atherosclerosis. LÄS MER

  7. 10. Antimicrobial peptides and proteins in innate immunity : emphasis on isolation, characterization and gene regulation

    Författare :Maria Tollin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Colon; vernix caseosa; rCRAMP; LL-37; cathelicidins; promoter studies;

    Sammanfattning : Antimicrobial peptides are endogenous antibiotics and effector molecules of Innate immunity. These peptides are mainly localised to epithelial linings and circulating neutrophils. They kill microbes by disruption of their membranes. The two main families of mammalian antimicrobial peptides are defensins and cathelicidins. LÄS MER