Sökning: "cathelicidin"
Visar resultat 11 - 15 av 28 avhandlingar innehållade ordet cathelicidin.
11. Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense
Sammanfattning : Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host. In humans, cathelicidins and defensins represent the major families of AMPs. LÄS MER
12. Antimicrobial peptides and pathogenic Neissera : experimental studies in mouse, man and rat
Sammanfattning : Antimicrobial peptides are important effector molecules of innate immunity. In this thesis, the focus is on antimicrobial peptides of the cathelicidin family, i.e. LL-37 in man, CRAMP in mouse and rCRAMP in rat. LÄS MER
13. Leukocyte activation in newborns in relation to prenatal stress
Sammanfattning : The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide LL-37 associated to different degrees of fetal stress and delivery modes. We know that delivery is associated to fetal stress including release of cortisol and cathecolamines. LÄS MER
14. Urinary tract infection : pathogenesis and complications
Sammanfattning : Urinary tract infections (UTI) are one of the most common infections in women and children worldwide. If not diagnosed and treated appropriately, it may lead to severe illness and long-term complications. The economic impact caused by UTI on society is significant. In addition, bacterial resistance to common antibiotics is spreading at a high rate. LÄS MER
15. Antimicrobial peptides in innate immunity : interactions with antibiotics and effects of post-translational modifications
Sammanfattning : Cationic antimicrobial peptides (AMPs) are important innate immunity factors contributing to the clearance of invading pathogens and immunomodulating immune responses. In this thesis, the focus is on AMPs of the cathelicidin family, i.e. the human LL-37 and the canine K9CATH. LÄS MER