Sökning: "castration therapy"

Visar resultat 21 - 25 av 28 avhandlingar innehållade orden castration therapy.

1. 21. Acupuncture treatment for hot flushes in women with breast cancer and men with prostate cancer

   Författare :Jessica Frisk; Mats Hammar; Hans Hjertberg; Anna-Clara Spetz; Leif Bergkvist; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Background: The group of women and men with a history of cancer and distressing hot flushes and sweating is growing. The flushes negatively affect Health Related Quality of Life (HRQoL), perhaps partially by disturbing sleep. Treatments that are effective, tolerable and safe need to be developed. LÄS MER

3. 22. MicroRNA expression profiles in prostate cancer bone metastases : functional effects of microRNA-23c, -375, and -4328

   Författare :Helena Järemo; Pernilla Wikström; Maria Brattsand; Anders Bergh; Elin Thysell; Guido Jenster; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer bone metastases; microRNA; metastatic subtypes; extracellular vesicles; Pathology; patologi;

   Sammanfattning : Non-coding microRNAs (miRNAs) function as post-transcriptional regulators of gene expression by interacting with messenger RNA. Dysregulation of miRNAs has many possible consequences, including tumor-suppressive or -promoting ones, and restoring or preventing the effects of miRNA alteration has therapeutic potential. LÄS MER

4. 23. Spatial transcriptome and epigenome analysis with focus on prostate cancer

   Författare :Maja Marklund; Joakim Lundeberg; Patrik Ståhl; Marc Friedländer; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spatial; Spatial Transcriptomics; Spatial ATAC; epigenomics; Biotechnology; Bioteknologi;

   Sammanfattning : Each cancer is unique, and therefore the use of general treatments are often suboptimal. If we can understand the mechanisms of cancer development, we might be able to develop effective treatments tailored to each patient. Our bodies are complex three-dimensional structures and how things are organized correlate with proper functioning. LÄS MER

5. 24. Studies on the molecular and functional properties of exosomes in the metastatic prostate cancer bone microenvironment

   Författare :Ioulia Vardaki; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Prostate cancer is the most common cancer type and the second leading cancer related cause of death worldwide in men. Prostate cancer patients initially respond to standard treatment (e.g., hormonal, surgery/irradiation) but about 30% of them will develop resistance and progress to metastatic Castration Resistant Prostate Cancer (mCRPC). LÄS MER

7. 25. Metastatic spinal cord compression in prostate cancer : clinical and morphological studies

   Författare :Sead Crnalic; Richard Löfvenberg; Anders Widmark; Anders Bergh; Sten Nilsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; bone metastasis; spinal cord compression; surgical treatment; survival prognosis; early diagnosis; androgen receptor; Orthopaedics; ortopedi; Pathology; patologi; Oncology; onkologi;

   Sammanfattning : Background: Bone metastases occur in most patients with advanced hormone-refractory prostate cancer causing pain, pathologic fractures, and spinal cord compression. Few studies specifically address surgical treatment of metastatic spinal cord compression (MSCC) in prostate cancer. LÄS MER