Sökning: "case-control association"

Visar resultat 1 - 5 av 334 avhandlingar innehållade orden case-control association.

1. 1. Molecular epidemiology approach : nested case-control studies in glioma and lymphoid malignancies

   Författare :Florentin Späth; Beatrice S. Melin; Carl Wibom; Ann Sofie Johansson; Ingvar Bergdahl; Ola Landgren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; B cell lymphoma; multiple myeloma; risk; repeated samples; prospective longitudinal study; nested case-control study; circulating sEGFR and sERBB2; circulating immune markers and growth factors; marker disease association; disease progression; NSHDS; Janus; linear mixed modeling; epidemiologi; Epidemiology; Oncology; onkologi;

   Sammanfattning : BACKGROUND: Nested case-control studies aim to link molecular markers with a certain outcome. Repeated prediagnostic samples may improve the evaluation of marker-disease associations. However, data regarding the benefit of repeated samples in such studies are sparse. LÄS MER

3. 2. Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors

   Författare :Håkan Lövkvist; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allelic association; candidate genes; case-control; family history; ischemic stroke; polymorphisms.;

   Sammanfattning : Background Stroke is a serious vascular disorder that comprises intracerebral hemorrhages, subarachnoid hemorrhages and ischemic stroke (IS). The etiology of stroke, including hereditary components induced by cellular mechanisms, is therefore a research field of vital importance. LÄS MER

4. 3. Efficient design and analysis of extended case-control studies

   Författare :Bénédicte Delcoigne; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The nested case-control design is widely used in epidemiology for its efficiency, as it combines the advantages of both cohort and case-control designs. This design is an extension of the matched case-control design, where the matching variable is the time of occurrence of the outcome. LÄS MER

5. 4. Prospective studies of hormonal and life-style related factors and risk of cancer

   Författare :Sara Wirén; Pär Stattin; Håkan Jonsson; Tanja Stocks; Alicja Wolk; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; epidemiology; androgens; risk factors; fatherhood status; dizygotic twins; height; cohort; case-control; prospective; Cancer Epidemiology; cancerepidemiologi;

   Sammanfattning : Background: Androgens are important in prostate cancer development but how circulating levels of androgens affect risk of prostate cancer of different aggressiveness is not clear. Being childless has been associated with a lower risk of prostate cancer, but it is not clear if this association is causal or a result of residual confounding. LÄS MER

7. 5. Case-control studies on risk factors for myeloid leukemias and myelodysplastic syndromes

   Författare :Jonas Björk; Avdelningen för arbets- och miljömedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiologic methods; bias epidemiology ; attributable fraction; smoking; hobbies; occupational exposure; chromosome aberrations; epidemiology; cytogenetic; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

   Sammanfattning : Case-control studies comprising telephone interviews for 333 cases of acute myeloid leukemia (AML), 226 cases of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), 330 cases of myelodysplastic syndromes (MDS), and matched controls were conducted. Information had to be obtained from next-of-kin much more often for cases (85%) than for controls (18%). LÄS MER