Sökning: "carl lindahl"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden carl lindahl.

  1. 1. Biomimetic Deposition of Hydroxyapatite on Titanium Implant Materials

    Författare :Carl Lindahl; Håkan Engqvist; Martin Andersson; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materialvetenskap; Materials Science;

    Sammanfattning : The clinical success of a bone-anchored implant is controlled by many factors such as implant shape, chemical composition, mechanical and surface properties. The surface properties (e.g. LÄS MER

  3. 2. Osteogenesis Imperfecta : Genetic and Therapeutic Studies

    Författare :Katarina Lindahl; Östen Ljunggren; Andreas Kindmark; Carl-Johan Rubin; David Sillence; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; OI; BMD; Genotype; Phenotype; Pharmaco-genetics; Bisphosphonate; Therapy; Gene-therapy; Mutation; Collagen; Collagen type I; Allele-specific silencing; siRNA; RNAi; COL1A1; COL1A2; Stroke; C-propeptide; Mineralization; Heterozygous disadvantage; Genetics; Genetik; Medicin; Medicine; Medical Genetics; Medicinsk genetik;

    Sammanfattning : Osteogenesis imperfecta (OI) is a heterogeneous disease of connective tissue, the cardinal symptom being fractures and severity ranging from mild to lethal. Dominant mutations in collagen I, encoded by COL1A1 and COL1A2, cause >90% of cases. LÄS MER

  4. 3. Modulation of PDGF Receptor Signaling via the Phosphatase SHP-2 and the Docking Protein Gab1

    Författare :Anders Kallin; Lars Rönnstrand; Carl-Henrik Heldin; Per Lindahl; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; PDGF; SHP-2; Gab1; chemotaxis; actin reorganization; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : x.... LÄS MER

  5. 4. Combination Therapies Targeting PDGF and VEGF Signaling Pathways in Solid Tumors

    Författare :Agnieszka Kłosowska-Wardęga; Carina Hellberg; Carl-Henrik Heldin; Per Lindahl; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN; Oncology; Onkologi;

    Sammanfattning : Vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) are independently involved in several cancer-associated mechanisms including autocrine stimulation of cancer cells, stimulation of tumor angiogenesis and regulation of interstitial fluid pressure (IFP). The scope of this thesis was to investigate the combinatory effect of anti-VEGF and anti-PDGF treatment on tumor angiogenesis and tumor IFP. LÄS MER

  7. 5. Human Behaviour in Social-Ecological Systems : Insights from economic experiments and agent-based modelling

    Författare :Caroline Schill; Therese Lindahl; Anne-Sophie Crépin; Johan Colding; Carl Folke; Juan Camilo Cárdenas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Human behaviour; Common-pool resources; Ecological complexity; Collective action; Sustainable resource use; Regime shifts; Thresholds; Uncertainty; Communication; Knowledge-sharing; Economic experiments; Laboratory and field experiments; Agent-based modelling; Complex adaptive systems; Social-ecological systems; Sustainability Science; vetenskap om hållbar utveckling;

    Sammanfattning : Progress towards sustainability requires changes in our individual and collective behaviour. Yet, our fundamental understanding of behaviour in relation to environmental change remains severely limited. LÄS MER