Sökning: "cardiac stem cells"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden cardiac stem cells.

  1. 1. Stem cells for cardiac regeneration

    Författare :Ivana Bulatović; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Recent studies have demonstrated a turnover of cardiomyocytes throughout the adult life. Whether this regenerative potential is due to proliferation and differentiation of resident stem cells or to the dedifferentiation of adult cardiomyocytes remains unclear. LÄS MER

  3. 2. Stem cells in the adult heart - 3D culture, isolation of side population cells and search for a stem cell niche

    Författare :Kristina Vukusic; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart; cardiac stem cells; Stem cell niche; Atrioventricular junction; Side population; 3D culture;

    Sammanfattning : Cardiac tissue shows a poor regenerative capacity. From 2003 reports, mostly based on animal models, have showed existence of stem cells also in the heart. Using 14C measurements, a slow but steady turnover of the cardiac cells was shown in humans, around 1%/year. As a source for this regeneration endogenous stem cells have been suggested. LÄS MER

  4. 3. Embryonic and adult cardiac stem cells : molecular, electrophysical and immunological characteristics for cardiac repair

    Författare :Rami Genead; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :human resident cardiac progenitor;

    Sammanfattning : Background: The concept of myocardial regeneration by means of stimulating the endogenous regenerative potential in situ is an attractive approach. This offers distinct advantages to stem cell implantation where the problems with engraftment and immune rejection are avoided. LÄS MER

  5. 4. Transcriptional profiling of human embryonic stem cells and their functional derivatives

    Författare :Jane Synnergren; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transcription; differentiation; human embryonic stem cells; gene expression; Naturvetenskap;

    Sammanfattning : Human embryonic stem cells (hESCs) represent populations of pluripotent, undifferentiated cells with unlimited replication capacity, and with the ability to differentiate into any functional cell type in the human body. Based on these properties, hESCs and their derivatives provide unique model systems for basic research on embryonic development. LÄS MER

  7. 5. On tissue engineering of pig, human, and non-human primate tissues

    Författare :Nikhil Nayakawde; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Decellularization; esophagus; heart; larynx; proteomics; recellularization; SILAC; stem cells; tissue engineering;

    Sammanfattning : Background: Demand for donor organs for transplantation has been increasing every year more than the actual supply of suitable donor organs. One of the major problems associated with allogeneic transplantation includes lifelong immunosuppression. LÄS MER