Sökning: "cardiac lipid metabolism"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden cardiac lipid metabolism.

  1. 1. Cardiac lipids and their role in the diseased heart

    Författare :Ismena Mardani; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular disease; Lipid droplets; Perilipins; Lipid accumulation; Metabolism; GlcCer;

    Sammanfattning : Lipids play an essential role within the heart as they are involved in energy storage, membrane stability and signaling. Changes in cardiac lipid composition and utilization may thus have profound effects on cardiac function. Importantly, the diseased heart is associated with intracellular metabolic abnormalities, including accumulation of lipids. LÄS MER

  3. 2. Cardiac lipid storage and metabolism following myocardial ischemia

    Författare :Christina Drevinge; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipid accumulation; Myocardial Ischemia; Lipid droplets; Perilipin2; Perilipin5;

    Sammanfattning : Myocardial ischemia is associated with cellular- and metabolic adjustments within the heart, including accumulation of lipids. Myocardial lipids are stored in cytosolic droplets, consisting of a core of neutral lipids surrounded by a complex surface containing proteins, such as perilipins. LÄS MER

  4. 3. Metabolic aspects of cardiac arrhythmias

    Författare :Sigfus Gizurarson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiologi; Electrofysiologi; Djurexperiment; Metabolism;

    Sammanfattning : Cardiac arrhythmias are an important cause of mortality and morbidity in patients with cardiac diseases. Sudden death due to ventricular tachycardia and fibrillation (VT/VF) in the setting of acute myocardial infarction (AMI) and heart failure (HF) is a frequent cause of premature death. LÄS MER

  5. 4. Myocardial creatine metabolism in experimental infarction and heart failure

    Författare :Malin Lindbom; Göteborgs universitet; []
    Nyckelord :Energy metabolism; Creatine; Congestive heart failure; Myocardial infarction; Ventricular arrhythmias; Cardiac remodeling; apolipoprotein B; Lipid metabolism;

    Sammanfattning : The failing heart is characterized by changes in structure, function and metabolism. All these changes are usually defined as pathologic remodelling. An important part of this negative remodelling process is disturbances in the myocardial energy metabolism. LÄS MER

  7. 5. Myocardial metabolism in experimental infarction and heart failure

    Författare :Truls Råmunddal; Göteborgs universitet; []
    Nyckelord :Myocardial metabolism; Heart failure; Myocardial infarction; Lipotoxic heart disease; Apolipoprotein B; Arrhythmias; Cardiac reserve; Creatine metabolism;

    Sammanfattning : Abstract The heart is an organ heavily dependent on exogenous lipids for the oxidative production of adenosine-triphosphate (ATP) and therefore maintenance of normal cellular energy homeostasis. However, high energy flux organs such as the heart must closely match lipid import and utilization or otherwise lipids will accumulate in the cardiomyocytes. LÄS MER