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Visar resultat 1 - 5 av 24 avhandlingar som matchar ovanstående sökkriterier.
1. Automation, hyphenation and multidimensional chromatography for PAH analysis : Analytical techniques to simplify sample complexity
Sammanfattning : One group of organic environmental pollutants which are potentially hazardous to human health is polycyclic aromatic hydrocarbons (PAHs). These compounds consist of two or more benzene rings in their structure among which benzo[a]pyrene (B[a]P) is classified as a human carcinogen. LÄS MER
2. A step forward in using QSARs for regulatory hazard and exposure assessment of chemicals
Sammanfattning : According to the REACH regulation chemicals produced or imported to the European Union need to be assessed to manage the risk of potential hazard to human health and the environment. An increasing number of chemicals in commerce prompts the need for utilizing faster and cheaper alternative methods for this assessment, such as quantitative structure-activity or property relationships (QSARs or QSPRs). LÄS MER
3. DNA lesions and carcinogenicity from the urban air pollutants 2- and 3-nitrobenzanthrone
Sammanfattning : In the early 1990's, Japanese doctors in urban areas discovered an increasing incidence of lung cancer among women, which was not attributed to a change in diet or smoking. This led to a growing investigation of urban air, and subsequently the discovery of 3-nitrobenzanthrone (3-NBA), a pollutant originating from diesel emissions. LÄS MER
4. Health of municipal sewage workers : Studies of cancer incidence, biomarkers of carcinogenicity and genotoxicity, and self reported symptoms
Sammanfattning : The occupational exposures of sewage workers are complex and variable, and include a great variety of biological and chemical agents. Previous research has focused mostly on infections and various symptoms among sewage workers, e.g. abdominal and respiratory symptoms. LÄS MER
5. Cellular effects of nickel and nickel oxide nanoparticles : focus on mechanisms related to carcinogenicity
Sammanfattning : There has been a rapid increase in the production and useage of nanomaterials during the last decade and therefore it is of great importance to properly investigate safety of these materials. This thesis specifically focuses on nickel (Ni) and nickel oxide (NiO) nanoparticles (NPs). LÄS MER