Sökning: "carboxylic groups"

Visar resultat 16 - 20 av 76 avhandlingar innehållade orden carboxylic groups.

  1. 16. Design and Synthesis of Inhibitors Targeting the Hepatitis C Virus NS3 Protease : Focus on C-Terminal Acyl Sulfonamides

    Författare :Robert Rönn; Anders Hallberg; Anja Sandström; Federico Corelli; Uppsala universitet; []
    Nyckelord :Pharmaceutical chemistry; hepatitis C virus; HCV; NS3 protease inhibitor; acyl sulfonamide; bioisostere; palladium; carbonylation; microwave; molybdenum hexacarbonyl; Farmaceutisk kemi;

    Sammanfattning : Hepatitis C is a global health problem that affects approximately 120–180 million people. This viral infection causes serious liver diseases and the therapy available suffers from low efficiency and severe side effects. Consequently, there is a huge unmet medical need for new therapeutic agents to combat the hepatitis C virus (HCV). LÄS MER

  3. 17. Lignin-Based Thermosets with Tunable Mechanical and Morphological Properties : A Study of Structure-Property Relationships

    Författare :Iuliana Ribca; Mats Johansson; Martin Lawoko; Stephan V. Roth; Mika Sipponen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Softwood; hardwood; technical lignin; solvent fractionation; allylation; thiol-ene thermosets; thioether linkage; wide-angle X-ray scattering; π-π stacking interactions; Barrträ; lövträ; tekniskt lignin; lösningsmedelsfraktionering; allylering; tiol-en-härdplaster; tioeterbindning; vidvinkelröntgenspridning; π-π staplingsinteraktioner; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Nowadays, there is an urgent need to decrease our dependence on fossilresources and shift towards the use of renewable resources for advancingsustainable development. Utilizing renewable and bio-based raw materials,such as lignocellulosic biomass, for designing new materials is a promisingapproach to promote this objective. LÄS MER

  4. 18. Self Assembled Monolayers for Quartz Crystal Microbalance based Biosensing

    Författare :Annica Myrskog; Bo Liedberg; Sofia Svedhem; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : The work in this thesis has been focused on developing surfaces for use in biosensor systems, especially for quartz crystal microbalances. The surfaces were prepared by adsorption of organosulfur molecules onto gold substrates, so called self assembled monolayers (SAMs). LÄS MER

  5. 19. Characterization of aluminum in environmental systems using X-ray absorption and vibrational spectroscopy : The importance of organic matter

    Författare :Kristoffer Hagvall; Torbjörn Karlsson; Per Persson; Lars Lövgren; Dan Berggren Kleja; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The fate and behavior of many metals in the environment are highly dependent on interactions with natural organic matter (NOM), which is abundant in most soils and surface waters. The complexation with NOM can influence the speciation of the metals by affecting their hydrolysis and solubility. LÄS MER

  7. 20. In vivo dosimetry of some alkylating agents as a basis for risk estimation

    Författare :Dan Segerbäck; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The present study concerns in vivo dosimetry of ultimate electrophilic reagents as a step in risk estimation of mutagenic and carcinogenic chemicals. The level of reaction products with nucleophilic groups in macromolecules could be used for dose determination. LÄS MER