Sökning: "carbopol gel"

Hittade 3 avhandlingar innehållade orden carbopol gel.

  1. 1. Polymer Gels as Pharmaceutical Dosage Forms : Rheological Performance and Physicochemical Interactions at the Gel-Mucus Interface for Formulations Intended for Mucosal Drug Delivery

    Författare :Helene Hägerström; Katarina Edsman; Arne Brodin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; gel; rheology; mucoadhesion; mucosal drug delivery; in situ gel; gellan gum; Carbopol; tensile strength; nasal mucosa; intranasal administration; dielectric spectroscopy; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Drug delivery to the nasal and ocular mucosa faces several obstacles. One of these is from the effective clearance mechanisms present in the nose and eye. Polymer gels with suitable rheological properties can facilitate the absorption of poorly absorbed drugs by increasing the contact time of the drug with the mucosa. LÄS MER

  3. 2. Electrochemical Methods for Drug Characterisation and Transdermal Delivery : Capillary Zone Electrophoresis, Conductometry, and Iontophoresis

    Författare :Nadia Merclin; Per Hansson; Sven Engström; Arto Urtti; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Capillary zone electrophoresis; precision conductometry; iontophoresis; passive diffusion; lidocaine; ALA; ALA-ester derivatives; sponge phase; carbopol gel; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : This thesis concerns the development and utilisation of techniques for characterisation and transdermal delivery of various systems for pharmaceutical applications.The degree of dissociation of drug molecules and the mobilities of the different species formed are essential factors affecting the rate of drug delivery by iontophoresis. LÄS MER

  4. 3. Drug Diffusion and Nano Excipient Formation Studied by Electrodynamic Methods

    Författare :Ulrika Brohede; Maria Strømme; Göran Frenning; Hans Leuenberger; Uppsala universitet; []
    Nyckelord :Functional materials; drug release; electrodynamic methods; diffusion; Funktionella material;

    Sammanfattning : New smart drugs demand new smart drug delivery systems and also new smart analysis methods for the drug delivery process and material characterization. This thesis contributes to the field by introducing a new electrodynamic approach for studying the drug diffusion proc-esses as well as the formation of a new type of drug delivery systems, the so called mesoporous nano excipients. LÄS MER