Sökning: "carbohydrate-deficient transferrin"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden carbohydrate-deficient transferrin.

  1. 1. New markers of alcohol consumption : development and evaluation of the clinical use of carbohydrate-deficient transferrin in serum and 5-hydroxytryptophol in urine

    Författare :Annette Voltaire Carlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alcohol drinking; 5-hydrogxytryptophol; 5-hydroxyindole-3-acetic acid; urine; human; ;

    Sammanfattning : Treatment of alcohol dependence and evaluation of treatment and research programs are often based on self-reports of the patients. Since the alcohol consumption pattern does not always relate to the reported behaviour there is a need for validation by reliable biochemical markers. LÄS MER

  3. 2. Human serum transferrin glycosylation pattern : population differences, analytical methodology and application as a biomarker for testing of alcohol abuse and CDG

    Författare :Jonas P Bergström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alcohol use and abuse is a major social and economic problem in many societies. Carbohydrate-deficient transferrin (CDT) is a widely used and highly specific biochemical alcohol marker of prolonged alcohol abuse. LÄS MER

  4. 3. Membrane-Assisted Isoform ImmunoAssay : Separation and determination of protein isoforms

    Författare :Maria Lönnberg; Carl G M Magnusson; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Bioteknik; Bioengineering; Bioteknik; Surface Biotechnology; ytbioteknik;

    Sammanfattning : Proteins exist in a variety of isoforms with minor differences, mostly due to their glycosylation patterns, which can modulate their biological functions. It seems to be of clinical relevance to measure the isoform-distribution.Thesis describes a novel technology named Membrane-Assisted Isoform ImmunoAssay (MAIIA). LÄS MER

  5. 4. Studies on the reliability of biomarkers for alcohol use and abuse

    Författare :Naama Modén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alcohol is consumed by the vast majority of the population, but prolonged excessive drinking is associated with various negative health and social consequences. It is therefore important to identify individuals with at-risk alcohol consumption, before it turns into abuse or dependence. LÄS MER

  7. 5. Development and application of an LC-MS method for the alcohol biomarker phosphatidylethanol (PEth) in blood

    Författare :Yufang Zheng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Objective biomarkers tracing alcohol consumption are demanded in many situations when alcohol drinking is in focus, e.g. during monitoring of patient in a treatment program, in forensic medicine, workplace testing or biochemical validation of self-report in research. LÄS MER