Sökning: "carbohydrate binding modules protein engineering affinity affinity maturation phage display specific"

Hittade 1 avhandling innehållade orden carbohydrate binding modules protein engineering affinity affinity maturation phage display specific.

  1. 1. Engineering protein-carbohydrate interactions - lessons from natural and evolved carbohydrate binding modules

    Författare :Laura von Schantz; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carbohydrate binding modules protein engineering affinity affinity maturation phage display specificity crystallography cellulose derivatives;

    Sammanfattning : Protein-carbohydrate interactions are of central role in all living organism. In the studies presented in this thesis several strategies for engineering such interactions have been investigated. In the first study the binding affinity of a carbohydrate binding module (CBM) was improved a 100-fold through affinity maturation. LÄS MER