Sökning: "carbazole"

Visar resultat 16 - 17 av 17 avhandlingar innehållade ordet carbazole.

  1. 16. Tryptophan photoproducts : regulation of CYP1A1 transcription and modulation of cell growth

    Författare :Yu-Dan Wei; Dieter Schrenk; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; toxikologisk genetik; Genetic Toxicology;

    Sammanfattning : The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in the regulation of many drug-metabolizing enzymes. The regulation of cytochrome P4501A1 (CYP1A1) has been most intensively studied. LÄS MER

  2. 17. Dynamic regulation of aryl hydrocarbon receptor function and activity by different stimuli

    Författare :Sandra Lücke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cells have to sense and adapt to changes in their surrounding environment. Most of the cellular responses to environmental and developmental stimuli are mediated by PAS (Per-ARNT-Sim) proteins. A member of this family of proteins is the aryl hydrocarbon receptor (AhR), a ligand-activated bHLH transcription factor and E3 ubiquitin ligase. LÄS MER