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Visar resultat 1 - 5 av 79 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Stress susceptibility, beta-blocker use and cancer survival

    Författare :Ruzan Udumyan; Katja Fall; Scott Montgomery; Fang Fang; Edoardo Botteri; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stress resilience; β-blockers; primary cancer; survival analysis; overall mortality; cancer-specific mortality; register-based cohort study;

    Sammanfattning : Accumulating evidence suggests that chronic stress may influence tumour biology through activation of neuroendocrine pathways and thus impair survival. However, measuring stressful exposures and their influence on health is challenging, partly due to substantial inter-individual variation in stress susceptibility. LÄS MER

  3. 2. Antibiotics use in relation to colorectal cancer risk, survival and postoperative complications

    Författare :Sai San Moon Lu; Bethany van Guelpen; Sophia Harlid; Jonas Ludvigsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; antibiotics; gut microbiome; dysbiosis; cancer-specific survival; surgical site infections; anastomotic leakage; register-based epidemiology; Cancer Epidemiology; cancerepidemiologi; Cancer Epidemiology; cancerepidemiologi; Oncology; onkologi; Surgery; kirurgi;

    Sammanfattning : Background: Growing evidence suggests that antibiotic-induced dysbiosis of gut microbiota potentially contributes to colorectal cancer development and oncological outcomes. However, the role of antibiotics in colorectal cancer incidence, survival and postoperative outcomes at a population level remains incompletely understood. LÄS MER

  4. 3. Colorectal cancer : Aspects of staging, treatment, recurrence and survival

    Författare :Åsa Collin; Joakim Folkesson; Wilhelm Graf; Malin Enblad; Marie-Louise Lydrup; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; recurrence; survival; staging; postoperative complications; Kirurgi; Surgery; Oncology; Onkologi;

    Sammanfattning : Colorectal cancer is the third most common malignancy in the world, and major breakthroughs have been made regarding both surgical and oncological treatment. Still, postoperative complications, such as perineal infections after abdominoperineal resection (APR), are a major cause of morbidity, and distant recurrence rate is nearly 20%. LÄS MER

  5. 4. Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function

    Författare :Filip Ahlmanner; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colon cancer; regulatory T cells; CD39; adenosine; immune checkpoint molecules; immunosuppression; MAIT cells; cytokines; cancer-specific survival;

    Sammanfattning : In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the balance between these two counteracting forces partly determines patient outcome. LÄS MER

  7. 5. Clinical and Biological Factors Related to Survival in Patients with Rectal Cancer

    Författare :Angeliki Kotti; Xiao-Feng Sun; Annica Holmqvist; Marie-Louise Lydrup; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Age; Radiotherapy; Rectal cancer; Skeletal muscle; SPARCL1; Statins; Survival; Visceral adipose tissue;

    Sammanfattning : Rectal cancer is a common malignancy within the gastrointestinal tract. Despite the advances in diagnosis and treatment of rectal cancer patients during the last decades, there are still many patients who die from their disease. LÄS MER