Sökning: "cancer vaccines"
Visar resultat 1 - 5 av 69 avhandlingar innehållade orden cancer vaccines.
1. Therapeutic Cancer Vaccines Targeting Molecules Associated with Tumor Angiogenesis
Sammanfattning : Induction of an endogenous antibody response by therapeutic vaccination could provide an alternative to cost-intensive monoclonal antibody-based treatments for cancer. Since the target of a cancer vaccine will most likely be a self-antigen, self-tolerance of the immune system must be circumvented. LÄS MER
2. Development of a Cancer Vaccine Targeting Tumor Blood Vessels
Sammanfattning : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. LÄS MER
3. Cancer Immunotherapy : Oncolytic viruses and CAR-T cells
Sammanfattning : Various forms of cancer immunotherapy have developed rapidly with improved survival and quality of life for cancer patients. Cancer immunotherapy aims to educate the patient’s immune system to eliminate cancer cells, including immune checkpoint inhibitors (ICIs), adoptive cell transfer (mostly T cells), oncolytic viruses (OVs) and cancer vaccines. LÄS MER
4. Cancer Immunotherapy : Evolving Oncolytic viruses and CAR T-cells
Sammanfattning : In the last decade cancer immunotherapy has taken huge strides forward from bench to bedside and being approved as drugs. Cancer immunotherapy harnesses the power of patient’s own immune system to fight cancer. LÄS MER
5. Vaccine Therapy of Colorectal Cancer Patients with Tumor Associated Antigens
Sammanfattning : In this thesis, two different vaccines were evaluated as adjuvant therapy for patients with colorectal cancer. The ability of the two candidate vaccines to generate antigen-specific cellular and humoral responses, respectively, was studied. LÄS MER