Sökning: "cancer stem cells"

Visar resultat 16 - 20 av 242 avhandlingar innehållade orden cancer stem cells.

  1. 16. Response mechanisms of normal hematopoietic cells and leukemic cells to genotoxic agents and novel therapeutic strategies

    Författare :Andreas Hedblom; Malmö Experimentell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic stem cells; genotoxic damage; cell cycle; leukemia; heme oxygenase; differentiation;

    Sammanfattning : Hematopoiesis is initiated by a rare population of hematopoietic stem cells (HSC) in the bone marrow (BM). HSCs give rise to red blood cells and white blood cells of myeloid and lymphoid lineages. LÄS MER

  3. 17. Not all those who wander are lost : A study of cancer cells by digital holographic imaging, fluorescence and a combination thereof

    Författare :Sofia Kamlund; Funktionell zoologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Digital holography; longitudinal tracking; breast cancer stem cells; salinomycin; EMT; Digital Holography; longitudinal tracking of individual cells; breast cancer cells; Breast cancer; Salinomycin; cancer stem cells; Fluorescence microscopy; EMT;

    Sammanfattning : Cells are commonly used in research to evaluate toxicity and efficiency of drugs. However, to further increase the usefulness of cells as well as the understandings of effects of different interventions, new methods must constantly be developed and refined. LÄS MER

  4. 18. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate

    Författare :Jens Ceder; Malmö (Abrahamsson) Urologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; somatostatin; transit amplifying cells; cell differentiation; adult stem cells; Prostate gland; prostatic benign hyperplasia; neuroendocrine cells; prostate cancer;

    Sammanfattning : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. LÄS MER

  5. 19. Regulation of normal and cancer cells as a base for cell cycle-targeted therapy

    Författare :Regina Miftakhova; Malmö Experimentell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell cycle regulation; cyclin A1; stem cells; stem cell niche; epigenetics; cancer;

    Sammanfattning : The majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. LÄS MER

  7. 20. The effect of intra-abdominal local anaesthetics following major gynaecological surgery. Clinical and experimental studies

    Författare :Jane M. Hayden; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Local anaesthetics; postoperative pain; hysterectomy; inflammation; ropivacaine toxicity; ovarian cancer; recovery; ovarian cancer cells;

    Sammanfattning : Background: Local anaesthetics (LA), in addition to inhibition of pain signalling, also have anti-inflammatory properties. In vitro studies have demonstrated anti-proliferative and cytotoxic effect of LAs on cancer cells when administered in therapeutic concentrations. LÄS MER