Sökning: "calpain"

Visar resultat 11 - 15 av 40 avhandlingar innehållade ordet calpain.

  1. 11. The role of the MAP- and SAP- kinase pathways in the survival, proliferation and death of Schwann cells of the injured sciatic nerve

    Författare :Lisa Mårtensson; Funktionell zoologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis concerns alterations in signal transduction in Schwann cells as a response to nerve injury as well as their survival, proliferation and death. Enzymes and transcription factors belonging to the mitogen activated protein kinase (MAPK) and the stress activated protein kinase (SAPK) pathways were studied. LÄS MER

  3. 12. Caspase-dependent and caspase-independent neuronal injury in the developing brain

    Författare :Changlian Zhu; Göteborgs universitet; []
    Nyckelord :hypoxia ischemia; neonatal; cell death; caspase; apoptosis-inducing factor; brain; apoptosis; autophagy; nitric oxide;

    Sammanfattning : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. LÄS MER

  4. 13. Design and development of electrochemical sensors with application in bioanalysis

    Författare :Kinga Zor; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bioanalysis; electrochemistry; sensor; biosensor; miniaturization; real sample; immunoassay; μTAS;

    Sammanfattning : There is a continuous search for reliable, robust, easy to use, portable and cost effective analytical tools with applications in food industry, biomedicine, environmental monitoring and homeland security. The main focus of this thesis is the development of electrochemical (bio)sensors and bioanalysis systems (to be applied in two major fields of interest: food & beverage industry and biomedical research) for monitoring key analytes in complex matrices, such as: meat samples, fermentation broths, and cell culture media. LÄS MER

  5. 14. Cisplatin-induced tumor cell death signaling and potentiation by energy metabolism inhibitors

    Författare :Linda Strandberg Ihrlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Treatment of cancer is associated with challenges including the tumor development of resistance. By elucidating intracellular signal transduction pathways elicited by therapy it is possible to identify structures and processes crucial for induction of cell death. The aim is to exploit this knowledge to improve treatment strategies. LÄS MER

  7. 15. Filamin A in Cardiovascular Remodeling

    Författare :Sashidar Bandaru; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Filamin A; Cardiovascular remodelling;

    Sammanfattning : Filamin A (FLNA) is a large actin-binding cytoskeletal protein that stabilizes actin networks and integrates them with cell membranes. FLNA is therefore important for cell motility and organ development. LÄS MER