Sökning: "caffeine"

Visar resultat 11 - 15 av 54 avhandlingar innehållade ordet caffeine.

  1. 11. Adenosine receptors and stress : studies using methylmercury, caffeine and hypoxia

    Författare :Olga Björklund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adenosine; adenosine receptors; knock-out mice; methylmercury; caffeine; hypoxia; cobalt chloride;

    Sammanfattning : Brain development is a precisely organized process that can be disturbed by various stress factors present in the diet (e.g. exposure to xenobiotics) as well as insults such as decreased oxygen supply. LÄS MER

  3. 12. Inflammation, caffeine and adenosine in neonatal hypoxic ischemic brain injury

    Författare :Max Winerdal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Brain injury during the neonatal period has potentially lifelong consequences for a child. Perinatal infections and inflammation can induce preterm birth and unfavorable cognitive development, Thus inflammation has received enthusiastic interest for potential therapeutic approaches seeking to protect the newborn brain. LÄS MER

  4. 13. Functional features of human cytochrome P450 1A2 : with special focus on caffeine and melatonin metabolism

    Författare :Anna Nordmark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Drug metabolism; CYP1A2; caffeine; melatonin; liver slices; in vitro methods;

    Sammanfattning : CYP1A2 is one of the major cytochrome P450 enzymes in the liver and metabolises drugs such as caffeine, clozapine, tacrine, and theophylline. CYP1A2 also has a role in chemical carcinogenesis due to its activation of procarcinogens, such as heterocyclic amines and arylamines. Caffeine is extensively used to assess CYP1A2 activity. LÄS MER

  5. 14. Importance of pharmacogenetic and environmental factors for variation in caffeine disposition : with special emphasis on CYP1A2, CYP2A6, NAT2 and XO

    Författare :Natasa Djordjevic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inter-individual variation in response to drugs conveys considerable risk of either therapy failure or drug toxicity. Caffeine, as one of the most frequently used psychoactive substances in the world, is not an exception, and both lack of effects and adverse reactions have been observed after usual doses. LÄS MER

  7. 15. Effects of post-treatments with hydroxyurea and caffeine in G2 on the frequency of chromosomal aberrations induced by physical and chemical agents in mammalian cells

    Författare :Kerstin Hansson; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER