Sökning: "c-jun"

Visar resultat 6 - 10 av 72 avhandlingar innehållade ordet c-jun.

  1. 6. Impulse noise and brain injury. An experimental study in rats

    Författare :Annette Säljö Moberg; Göteborgs universitet; []
    Nyckelord :apoptosis; astrocytes; brain injury; blast; c-Fos; c-Jun; c-Myc; impulse noise; ; neurons; neurofilament; NSE; rat and S-100;

    Sammanfattning : Abstract. Pressure waves, experienced as impulse noise, affect many body organs, although most attention has been paid to the inner ear. Impulse noise is produced by e.g. LÄS MER

  3. 7. Regulation of vascular function by fluid mechanical forces. Development of a new vascular experimental platform for integrative physiological and molecular biological studies of living conduit vessels

    Författare :Li-Ming Gan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; perfusion model; endothelium; smooth muscle cells; shear stress; pressure; nitric oxide; endothelin-1; vascular endothelial growth factor; c-jun; c-fos; real-time PCR; NO probe.;

    Sammanfattning : The vascular endothelium is a multifunctional interface between blood flow and target organs and is continuously exposed to fluid mechanical forces such as shear stress, compressive, and tensile forces. Both in vivo and in vitro data indicate that biomechanical forces exert important modulating effects on key vascular functions. LÄS MER

  4. 8. Assessment of experimental neurotrauma

    Författare :Ying-Lai Huang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Impulse noise; diffuse brain injury; focal brain injury; closed head injury; NSE; S-100; GFAP; apoptosis; astrocytosis; glutamate; c-JUN; rotational acceleration; CSF;

    Sammanfattning : Model systems of closed head injury are designed to replicate aspects of traumatic brain injury, ischemia and epilepsy in man. The aim of this thesis was to (1) develop sensitive systems enabling analyses of the biochemical reactions, as reflected by leakage of marker compounds to the cerebrospinal fluid (CSF); and (2) develop and assess a new model for closed head injury and associated dynamic changes in the brain cell. LÄS MER

  5. 9. Inflammatory responses of gingival fibroblasts in the interaction with the periodontal pathogen Porphyromonas gingivalis

    Författare :Eleonor Palm; Torbjörn Bengtsson; Hazem Khalaf; Gunnel Svensäter; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Porphyromonas gingivalis; fibroblasts; CXCL8; TGF-β1; IL-6; SLPI; IDO; c-JUN; PKC; p38; periodontitis; Biomedicin; Biomedicine;

    Sammanfattning : .... LÄS MER

  7. 10. Prostaglandin E synthases in periodontitis-affected gingival tissue and in gingival fibroblasts

    Författare :Tove Båge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :c-Jun N-terminal kinase;

    Sammanfattning : Periodontitis is a chronic inflammatory disease resulting in the destruction of the tissue and alveolar bone supporting the teeth and leading ultimately to tooth loss. Prostaglandin E2 (PGE2) is an important inflammatory mediator in the pathogenesis of periodontitis. LÄS MER