Sökning: "c-erbB-2"

Hittade 4 avhandlingar innehållade ordet c-erbB-2.

  1. 1. Prognosis in carcinoma in situ of the breast

    Författare :Fredrik Wärnberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Breast carcinoma; ductal carcinoma in situ; lobular carcinoma in situ; prognosis; histopathological grade; p53; c-erbB-2; Ki 67; Bcl-2; hormone receptors; angiogenesis; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : The incidence of breast cancer is rising steadily in Sweden and the proportion of carcinoma in situ (CIS) has increased appreciably, most likely due to mammography screening. The aim of this study was twofold: (1) to examine risk factors for subsequent invasive breast carcinoma and breast cancer death after primary ductal carcinoma in situ (DCIS) and (2) to study the biology in the progress between in situ and invasive carcinoma. LÄS MER

  3. 2. HER2 and TP53 in human breast cancer : studies of methods and prognostic value

    Författare :Jenny Bergqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; HER2; c-erbB-2; TP53; tamoxifen; endocrine resistance;

    Sammanfattning : Prognostic and predictive factors are needed for tailored therapy strategies, aimed at reducing breast cancer relapse and improving survival. The present arsenal of such factors is insufficient. LÄS MER

  4. 3. Prognostic Factors in Breast Cancer

    Författare :Marie Sundquist; Nils Wilking; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Breast cancer is increasing in the industrialised countries. Due to early detection and adjuvaut treatment with radiotherapy, hormones and chemotherapy, mortality has decreased. The different adjuvant treatments have adverse effects. LÄS MER

  5. 4. Risk factors for ipsilateral breast tumor recurrence and uncontrolled local disease

    Författare :Kristina Dalberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; ipsilateral breast tumor recurrence; uncontrolled local disease; risk factors;

    Sammanfattning : The aims of the study were to assess intrinsic and treatment related risk factors for ipsilateral breast tumor recurrence (IBTR) and uncontrolled local disease (ULD) following breast-conserving surgery of early-stage invasive breast cancer. In a cohort of 759 women with T1-T2 tumors risk factors were evaluated. LÄS MER