Sökning: "building block method"

Visar resultat 6 - 10 av 44 avhandlingar innehållade orden building block method.

1. 6. Natural products from nonracemie building blocks : synthesis of pine sawfly pheromones

   Författare :Michael Larsson; Torbjörn Norin; Gunnar Westman; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Total synthesis; diastereoselective addition; dimethylzinc; Lewis acid; alkyllithium; Organisk kemi; Organic chemistry; Organisk kemi;

   Sammanfattning : This thesis describes a number of synthetic approaches for obtaining chiral, enantiomerically pure natural products, in particular some semiochemicals. This has been accomplished by using various strategies; by starting from compounds from the chiral pool, by using chiral auxiliaries, via enzymatic resolutions or by chemical asymmetric synthesis. LÄS MER

3. 7. Digital block transmission and time-of-flight estimation : receiver design and performance analysis

   Författare :Håkan B. Eriksson; Luleå tekniska universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Signalbehandling; Signal Processing;

   Sammanfattning : This thesis is concerned with signal processing aspects of digital block transmission and time-of-flight estimation. Receivers are derived and analysed based on the assumption that the received signals have been corrupted with additive Gaussian noise and linear distortion. LÄS MER

4. 8. Transition Metal-Mediated Selective Functionalizations of Bio-Derived Building Blocks

   Författare :Petter Dunås; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phenols; Heck reaction; microbial arene oxidation; green chemistry; domino reactions; chirality transfer; palladium; metal carbonyl; azulenes; renewable resources; iron;

   Sammanfattning : In order to transition to a more sustainable chemical industry, it is necessary to replace the fossil starting materials that are largely used today with renewable ones. Starting materials available from abundant natural sources, or which can be efficiently produced via a biotransformation, are of high interest in this regard. LÄS MER

5. 9. Selective Transformations of Allylic Compounds and Enol Derivatives : Synthesis of Fluorinated and Nitrogenated Scaffolds

   Författare :Víctor García-Vázquez; Belén Martín‐Matute; Mario Waser; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fluorinated compounds; Base catalysis; Ion-Pair; Isomerization; Pd catalysis; Method development; Hypervalent iodine III ; Organic Chemistry; organisk kemi;

   Sammanfattning : In this thesis, new synthetic methods to give access to molecules having fluorinated scaffolds and other polar functional groups have been developed. The methods give access to highly valuable organic compounds that may serve as building blocks in the synthesis of functionalized drug candidates. LÄS MER

7. 10. Studies towards a method for incorporation of 3'-deoxy-3'-C-methylenephosphonate linkages into oligonucleotides

   Författare :Anna Winqvist; Colin B. Reese; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic Chemistry; organisk kemi;

   Sammanfattning : Synthetic strategies towards 3’-deoxy-3’-C-methylenephosphinate building blocks were explored. The key transformations involved stereoselective hydroboration of 1-[2-O-(tert-butyldimethylsilyl-5-O-(4-methoxytrityl)-3-deoxy-3-C-methylene- ß -D-erythro-pentofuranosyl]uracil to give the corresponding 3’-deoxy-3’-C- hydroxymethyl derivative with ribo-configuration, as well as the further conversion into a precursor with a suitable leaving group, e. LÄS MER