Sökning: "brown adipose tissue"

Visar resultat 6 - 10 av 80 avhandlingar innehållade orden brown adipose tissue.

  1. 6. Who is Who in the Adipose Organ : A look at the Heterogeneity of Adipocyte Biology

    Författare :Jasper de Jong; Jan Nedergaard; Christian Wolfrum; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipose tissue; Adipocyte; Brown; White; Brite Beige; Physiology; fysiologi; Physiology;

    Sammanfattning : The increasing prevalence of obesity and related health complications, such as type 2 diabetes, cardiovascular disease and cancer, demands thorough investigation of the underlying processes. One of the key tissues investigated in this context is adipose tissue. LÄS MER

  3. 7. Brown is the new white: consequences of white adipose tissue alterations in Huntington's disease

    Författare :Andy Mccourt; Biomarkörer vid hjärnsjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s disease; weight loss; white adipose tissue; brown adipose tissue; peripheral symptoms; R6 2 mice; UCP1; CREB1; gene expression;

    Sammanfattning : Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. LÄS MER

  4. 8. Energy flow and metabolic efficiency attributed to brown adipose tissue

    Författare :Gabriella von Essen; Jan Nedergaard; Susanne Klaus; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brown adipose tissue; BAT; UCP1; diet-induced thermogenesis; DIT; obesity; high-fat diet; energy expenditure; fysiologi; Physiology;

    Sammanfattning : The large capacity of brown adipose tissue (BAT) to expend energy as heat makes it an interesting potential player in weight regulation and other metabolic conditions. This is of particular interest as it has been recognized that adult humans possess BAT. LÄS MER

  5. 9. Dietary, Pharmacological and Environmental Effects on Brown Adipose Tissue

    Författare :Erik Lindsund; Tore Bengtsson; Jan Nedergaard; Karsten Kristiansen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Obesity; brown adipose tissue; uncoupling protein 1; moderate cold exposure; calorimetry; thyroxine; dietary protein; thermic effect of food; diet-induced thermogenesis; adrenergic stimulation; mice; physiology; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Obesity is a common health issue; over 12 % of the adult world population have obesity. Obesity has many co-morbidities including cardo-vascular diseases and diabetes. Obesity is the result of chronic positive energy balance, eating too much and expending too little. LÄS MER

  7. 10. The secretome of brown adipose tissue

    Författare :Ida R. Hansen; Jan Nedergaard; Francesco Villarroya; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fysiologi; Physiology;

    Sammanfattning : Brown adipose tissue has long been known for its heat-producing capacity, but less is known about its possible effects as a secretory organ. This thesis summarizes information about presently known factors secreted from brown adipose tissue and about their actions. We were able to add factors to the list by the use of a signal-sequence trap method. LÄS MER