Sökning: "bronchial responsiveness"

Visar resultat 11 - 15 av 22 avhandlingar innehållade orden bronchial responsiveness.

  1. 11. The contribution of eosinophils and mediators in allergic inflammation

    Författare :Annika Roquet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :allergic inflammation; eosinophils; bronchial hyperresponsiveness; histamine; leukotrienes; antihistamine; leukotriene-antagonist; low-dose challenge;

    Sammanfattning : The aim of the present work was to investigate the development of allergic inflammation. For this purpose human experimental challenge models in skin, nose and bronchi were used as well as pharmacological interventions. A variety of inflammatory cells and mediators have been suggested as important in the pathogenesis of allergic inflammation. LÄS MER

  3. 12. Effects of glucocorticoids or beta 2-agonists on inflammatory responses induced by organic dust in vitro and in vivo

    Författare :Alexandra Ek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Exposure of healthy subjects in a swine barn causes an acute inflammatory response in the airways and an increase in bronchial responsiveness to methacholine. The aim of this thesis was to study the mechanisms by which glucocorticoids or Beta2-agonists interfere with the inflammatory response following swine house dust-exposure both in vitro and in vivo. LÄS MER

  4. 13. Asthma in adolescents, during the transition from child to adult, effects on physiological parameters and health related quality of life

    Författare :Kerstin Sundell Bergström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adherence; adolescents; asthma; females; physical exercise; Quality of Life; transition; young adults.;

    Sammanfattning : The aims of this thesis were to evaluate physiological and allergic aspects and consequences of asthma and possible correlation between Health Related Quality of Life (HRQOL) and atopy, lung function, bronchial hyper-responsiveness and regular physical exercise. Possible risk factors for deterioration among patients in their late teenage years prior to and following transfer to adult healthcare were examined. LÄS MER

  5. 14. A study on pharmacokinetic and pharmacodynamic effects of salbutamol-isomers

    Författare :Kerstin Naidu Sjöswärd; Göran Hedenstierna; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Astma är en kronisk inflammatorisk luftvägssjukdom som förekommer i hög - och enligt rapporter ökande - frekvens världen över. Defmitionen av astma inkluderar varierande luftvägsobstruktion och ökad bronkiell reaktivhet gentemot olika stimuli. LÄS MER

  7. 15. Inflammatory Markers, Respiratory Diseases, Lung Function and Associated Gender Differences

    Författare :Inga Sif Ólafsdóttir; Christer Janson; Anders Blomberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C-reactive protein; matrix metalloproteinase-9; tissue inhibitor of metalloproteinase-1; COPD; FEV1; FVC; lung function; systemic inflammation; gender differences; Lungmedicin; Lung Medicine;

    Sammanfattning : Systemic inflammation is associated with impaired lung function. Inflammation is part of asthma and chronic obstructive pulmonary disease (COPD), but the local and systemic inflammatory pattern differs. LÄS MER