Sökning: "brimonidine"

Hittade 3 avhandlingar innehållade ordet brimonidine.

  1. 1. Experimental Injury to the Visual System : Molecular Studies of the Retina

    Författare :Ulrika Lönngren; Finn Hallböök; Fredrik Ghosh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retina; injury; ischemia; gene expression; brimonidine; alpha-2-adrenergic agonist; neuroprotection; growth factors; apoptosis; Müller cells; Neuroscience; Neurovetenskap;

    Sammanfattning : Retinal ganglion cells play a crucial role in the relay of visual signals from the eye to the brain. This cell type is affected and eventually lost in the eye disease glaucoma, resulting in progressive and irreversible loss of vision. LÄS MER

  3. 2. Modulation of the Progenitor Cell and Homeostatic Capacities of Müller Glia Cells in Retina : Focus on α2-Adrenergic and Endothelin Receptor Signaling Systems

    Författare :Mohammad Harun-Or-Rashid; Finn Hallböök; Per Ekström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha2-adrenergic receptor; Brimonidine; Brn3a; Dedifferentiation; Endothelin; EGFR; ERK1 2; Neuroprotection; NMDA; MIO-M1 human Müller cell; Müller cells; Retina; Retinal ganglion cells; Src-kinase; Transactivation.; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Müller cells are major glial cells in the retina and have a broad range of functions that are vital for the retinal neurons. During retinal injury gliotic response either leads to Müller cell dedifferentiation and formation of a retinal progenitor or to maintenance of mature Müller cell functions. LÄS MER

  4. 3. α1- and α2-Adrenoceptors in the Eye : Pharmacological and Functional Characterization

    Författare :Anna Wikberg-Matsson; Thomas Mittag; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; α1-adrenoceptor subtypes; α2-adrenoceptor subtypes; iris; ciliary body; choroid; retina; ciliary artery; Neurovetenskap; Neurology; Neurologi; Ophtalmology; oftalmiatrik;

    Sammanfattning : α1- and α2-Adrenoceptors are involved in various physiological events in the eye: blood flow regulation, aqueous humor dynamics and pupil regulation. The α1- and α2-adrenoceptors can be further subdivided into six subtypes (α1A, α1B, α1D, α2A , α2B, and α2C ). LÄS MER