Sökning: "breast cancer induction"

Visar resultat 11 - 15 av 52 avhandlingar innehållade orden breast cancer induction.

  1. 11. Functional genetic studies of Psoriasin: a potential biomarker for breast cancer with a poor prognosis

    Författare :Stina Petersson; Göteborgs universitet; []
    Nyckelord :Psoriasin; Breast cancer; Reactive oxidant species; NF-κB; IFNγ; STAT1; ICAM-1; MUC1; CD24;

    Sammanfattning : Breast cancer is the most common malignancy in women. There is a high degree of heterogeneity in breast tumours and they can be divided into subtypes that have different expression pattern and clinical outcome. Ductal Carcinoma in situ (DCIS) is regarded as a precursor of invasive ductal breast cancer. LÄS MER

  3. 12. Diet and postmenopausal breast cancer - With a focus on low-grade inflammation

    Författare :Joana Alves Dias; Nutritionsepidemiologi; []
    Nyckelord :Oxidative stress; low-grade inflammation; Biomarkers of inflammation; cytokines; ICC; variation; diet; dietary recommendations; diet quality index; food patterns; reduced rank regression; obesity; CVD; postmenopausal breast cancer; epidemiology; cross sectional; nested case-control;

    Sammanfattning : Diet-breast cancer studies have shown that “healthy eating patterns” are associated with decreased risk whereas unhealthy patterns (especially those including alcohol) are associated with increased risk, particularly in postmenopausal women. The potential mechanisms behind the observed associations are still under investigation. LÄS MER

  4. 13. The mechanism of HAMLET-induced cell death - cellular signalling, oncogenes and clinical perspectives

    Författare :Petter Storm; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HAMLET; cancer; cell death; c-Myc; glycolysis; hexokinase; ion channels; p38 MAPK; lipids; colon cancer; beta-catenin;

    Sammanfattning : Despite recent advances in cancer treatment, truly innovative approaches are required to move beyond the modest benefits achieved to date. HAMLET is a human protein-lipid complex originally discovered in breast milk able to kill a wide range of tumour cells while leaving healthy, differentiated cells unaffected. LÄS MER

  5. 14. Role of TGFβ-induced hyaluronan-CD44 signaling in cancer progression

    Författare :Constantinos Kolliopoulos; Evi Heldin; Aristidis Moustakas; Jonathan Sleeman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hyaluronan; CD44; TGFβ; cancer; EMT; signal transduction; transcriptional regulation;

    Sammanfattning : Hyaluronan, a prevalent glycosaminoglycan of the extracellular space often accumulates in pathological conditions, such as chronic inflammation, infection, and cancer. Hyaluronan synthase HAS2 has been responsible for the synthesis and deposition of hyaluronan in a variety of tumors. LÄS MER

  7. 15. Biological and therapeutic aspects of breast cancer progression

    Författare :Karthik Govindasamy Muralidharan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Breast cancer is the second leading cause of cancer related death in women worldwide1. Although majority of primary breast cancers are curable with current treatment strategies, treatment outcome of metastatic breast cancer is dismal. LÄS MER