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Visar resultat 1 - 5 av 115 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Towards a deeper understanding of the human brain

   Författare :Evelina Sjöstedt; Mathias Uhlén; Jan Mulder; Caroline Kampf; Elly Hol; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain; organization; RNA; classification; mapping; proteins; antibodies; Bioteknologi; Biotechnology;

   Sammanfattning : Identifying the proteome variation in different parts of the body provides fundamental molecular details, enabling further findings and mapping of tissue specific proteins. By combining quantitative transcriptomics with qualitative antibody based proteomics, the Human Protein Atlas (HPA) project aims to protein profile each human protein-coding gene. LÄS MER

3. 2. Human brain function evaluated with rCBF-SPECT : memory and pain related changes and new diagnostic possibilities in Alzheimer’s disease

   Författare :Torbjörn Sundström; Katrine Riklund; Rimma Danielsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain imaging; rCBF; SPECT; early diagnosis; brain atlas; HMPAO; Alzheimer´s disease; Whiplash; neuropsychological function; episodic memory; Diagnostic radiology; Diagnostisk radiologi;

   Sammanfattning : The aim of this doctoral thesis was to study the influence of memory, pain, age and education on the regional cerebral blood flow (rCBF), i.e. brain function, in early Alzheimer's disease (AD) and in chronic neck pain patients in comparison to healthy controls and in healthy elderly per se. LÄS MER

4. 3. The aging brain and changes in cognitive performance : Findings from morphometry and quantitative susceptibility mapping of iron

   Författare :Ninni Persson; Håkan Fischser; Kristine B. Walhovd; Stockholms universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; brain aging; volumes; ndividual differences; QSM; cognitive aging; iron; episodic memory; fluid-; crystalized abilities; sex differences; gender differences; Psychology; psykologi;

   Sammanfattning : Brain aging is a heterogeneous phenomenon, and this thesis illustrates how the course of aging can vary within individuals over time and between individuals as a function of age, sex, and genetic variability. We used two contrasts from magnetic resonance imaging (MRI), namely spin-lattice T1-weighted imaging, and quantitative susceptibility mapping (QSM) from gradient-echo images, to picture the aging brain, by means of morphometric measures and brain-iron concentrations. LÄS MER

5. 4. Mapping prosody onto the lexicon : Memory traces for lexically specified prosodic information in the brain

   Författare :Hatice Zora; Mattias Heldner; Iris-Corinna Schwarz; Valéria Csépe; Stockholms universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; lexical access; prosody; neuroimaging; electroencephalography; event-related potentials; memory trace; typology; English; Turkish; Swedish; Linguistics; lingvistik;

   Sammanfattning : Lexical access, the matching of auditory information onto lexical representations in the brain, is a crucial component of online language processing. To understand the nature of lexical access, it is important to identify the kind of acoustic information that is stored in the long-term memory and to study how the brain uses such information. LÄS MER

7. 5. Mapping brain circuits : anatomy, connectivity and function

   Författare :Yang Xuan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : To decipher neural circuits anatomy is the central basis for all kinds of neurobiological studies. Here in this thesis, I will start with extensive overview of the current methods that have been intensively employed in labeling and mapping neurons and neuronal activities, including tracing techniques, imaging/recording systems and manipulation tools. LÄS MER