Sökning: "brain circulation"

Visar resultat 6 - 10 av 72 avhandlingar innehållade orden brain circulation.

  1. 6. Intranasal Cooling for Cerebral Hypothermia Treatment

    Författare :Lucian Covaciu; Sten Rubertsson; Jan Weis; Peter Andrews; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Selective brain cooling; cerebral hypothermia; therapeutic hypothermia; cardiac arrest; stroke; traumatic brain injury; brain temperature; magnetic resonance spectroscopy; trigeminal reflex; Intensive care; Intensivvård; Radiology; Radiologi; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : The controlled lowering of core body temperature to 32°C to 34°C is defined as therapeutic hypothermia (TH). Therapeutic hypothermia has been shown to improve neurological outcome and survival in unconscious patients successfully resuscitated after cardiac arrest. LÄS MER

  3. 7. Acupuncture in reproductive medicine. Applications in human assisted reproduction and aspects of clinical and experimental neuroendocrinology

    Författare :Elisabet Stener-Victorin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electro-acupuncture; blood flow impedance; circulation; uterine artery; in-vitro fertilization; oocyte aspiration; polycystic ovary syndrome; experimentally induced PCO; anovulation; gonadotropins; steroids; neuropeptides; b-endorphin; nerve growth factor; corticotropin-releasing factor.;

    Sammanfattning : The use of acupuncture in the area of reproductive medicine is relatively new, and it has been rather poorly investigated in the past. When muscle afferents are stimulated by acupuncture in somatic segments related to the innervation of the ovaries and the uterus, functional changes occur in the neural substrate that may influence reproductive function and result in peripheral, segmental and central effects. LÄS MER

  4. 8. Cerebral Perfusion and Metabolism during Experimental Extracorporeal Circulation

    Författare :Ove Jonsson; Stefan Thelin; Fredrik Lennmyr; Sven-Erik Ricksten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral perfusion; Experimental brain research; Experimentell hjärnforskning; Thoraxkirurgi; Thorax Surgery;

    Sammanfattning : Neurologic injuries are major causes of mortality and morbidity after cardiac surgery. This thesis aimed to investigate cerebral metabolism and perfusion abnormalities in pigs during hypothermic circulatory arrest, selective antegrade cerebral perfusion (SACP) and extracorporeal circulation following progressive venous stasis. LÄS MER

  5. 9. Pericyte Influence on Drug Delivery Across the Blood-Brain Barrier : Implications for Therapy of Neurodegenerative Diseases

    Författare :Nebojsa Mihajlica; Margareta Hammarlund-Udenaes; Christer Betsholtz; William Elmquist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; pericytes; pericyte-deficiency; pharmacokinetics; small-molecular drugs; drug distribution; transporters; P-glycoprotein; tyrosine kinase inhibitors; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Sammanfattning : The blood-brain barrier (BBB) represents a complex interface between the brain parenchyma and systemic blood circulation, strictly controlling exchange of substances between the two sites. Pericytes are mural cells located on the abluminal membrane of the brain endothelium, involved in BBB formation and maintenance. LÄS MER

  7. 10. Signaling to the immature brain - Choroid plexus, insulin-like growth factor 1 and extracellular vesicles

    Författare :Niklas Ortenlöf; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGF-1; Choroid plexus; Immature brain; Extracellular vesicle; CSF; Preterm infants;

    Sammanfattning : Extremely preterm infants (i.e., born below 28 gestational weeks), are at high risk of developing brain morbidities including intraventricular hemorrhage (IVH) and neurodevelopmental impairment. Despite over 50 years of research, there is currently no effective therapy available for preventing IVH. LÄS MER