Sökning: "brain circulation"

Visar resultat 1 - 5 av 65 avhandlingar innehållade orden brain circulation.

  1. 1. Aspects of central integrative and efferent mechanisms in cardiovascular reflex control

    Författare :Göran Wennergren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Afferent Pathways; physiology; Animals; Arteries; physiology; Blood Circulation; Blood Pressure; Brain; physiology; Cats; Chemoreceptor Cells; physiology; Coronary Circulation; Coronary Vessels; physiology; Efferent Pathways; physiology; Electric Stimulation; Female; Heart; innervation; physiology; Heart Rate; Hypothalamus; physiology; Male; Pressoreceptors; physiology; Reflex; Sympathetic Nervous System; physiology; Ventricular Function;

    Sammanfattning : .... LÄS MER

  2. 2. Brain-sparing Circulation in Growth-restricted Human Fetuses

    Författare :Jing Fu; Urogynekologi och reproduktionsfarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; gynaecology; andrology; reproduction; sexuality; Fetal growth-restriction.; Brain-sparing.; Oxytocin challenge test.; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : The aim of the studies was to explore fetal circulatory changes relative to development of brain-sparing flow (BSF) in growth-restricted fetuses exposed to acute hypoxic stress, as provoked by uterine contractions during an oxytocin challenge test (OCT).(1) In fetuses with a normal cerebral circulation during basal conditions, signs of an acute hyperperfusion in both the arterial and venous cerebral vascular systems were demonstrated in response to acute hypoxic stress; (2) Fetuses with an already established BSF showed no further ability of brain-sparing during acute hypoxic stress; (3) In venous cerebral vessels of fetuses with established BSF, the flow responses to hypoxic stress were equivocal, indicating different reactions in areas drained by different veins, or a deranged physiological vascular response; (4) Blood flow changes occurred synchronized in the middle and anterior cerebral arteries when fetuses with an intact cerebral circulation were exposed to hypoxic stress; (5) When fetuses with an established BSF showed no further changes in the middle cerebral artery, no changes were found in the anterior cerebral artery either. LÄS MER

  3. 3. Drug Delivery to the Brain by Liposomes : Understanding Factors Governing Delivery Outcomes In Vivo

    Författare :Yang Hu; Margareta Hammarlund-Udenaes; Teresa Dalla Costa; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanocarrier; liposome; blood-brain barrier; brain delivery; formulation; methotrexate; diphenhydramine; microdialysis; pharmacokinetics; model-based approach; Farmaceutisk vetenskap; Pharmaceutical Science; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Sammanfattning : The blood-brain barrier (BBB) is the primary obstacle for efficient drug delivery to the central nervous system (CNS). One promising strategy to enhance brain delivery is to utilize nanocarriers (NC), e.g., liposomes, encapsulating CNS drugs. LÄS MER

  4. 4. Cerebral circulation and the sympathetic nervous system in patients with traumatic brain injury or subarachnoid hemorrhage

    Författare :Silvana Naredi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :traumatic brain injury; brain edema; microcirculation; intracranial pressure; epo-prostenol; norepinephrine; subarachnoid hemorrhage; sympathetic nervous system; clonidine;

    Sammanfattning : Maintenance of adequate cerebral microcirculation is necessary to avoid cerebral ischemia after severe traumatic brain injury and non-traumatic subarachnoid hemorrhage. After severe traumatic brain injury the blood-brain-barrier is disrupted and transcapillary leakage will contribute to the development of vasogenic brain edema. LÄS MER

  5. 5. Intranasal Cooling for Cerebral Hypothermia Treatment

    Författare :Lucian Covaciu; Sten Rubertsson; Jan Weis; Peter Andrews; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Selective brain cooling; cerebral hypothermia; therapeutic hypothermia; cardiac arrest; stroke; traumatic brain injury; brain temperature; magnetic resonance spectroscopy; trigeminal reflex; Intensive care; Intensivvård; Radiology; Radiologi; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : The controlled lowering of core body temperature to 32°C to 34°C is defined as therapeutic hypothermia (TH). Therapeutic hypothermia has been shown to improve neurological outcome and survival in unconscious patients successfully resuscitated after cardiac arrest. LÄS MER