Sökning: "brain aging"
Visar resultat 1 - 5 av 115 avhandlingar innehållade orden brain aging.
1. The aged brain : structural changes and cognitive function
Sammanfattning : .... LÄS MER
2. Telomeres and the brain : an investigation into the relationships of leukocyte telomere length with functional and structural attributes of the brain
Sammanfattning : Telomeres are the outermost parts of linear chromosomes. They consist of tandemly repeated non-coding short nucleotide sequences (TTAGGG in all vertebrates), in humans spanning over the last 2 to 15 kilobase pairs of the chromosome. Due to the end-replication problem, telomeres shorten with each cellular division. LÄS MER
3. The architecture of the aging brain : functional reorganization, structural changes, and the role of dopamine receptors
Sammanfattning : Aging is associated with reorganization of functional brain architecture, potentially leading tocognitive decline in older age. However, the mechanisms responsible for alterations in functionalbrain architecture remain poorly understood. LÄS MER
4. The aging brain and changes in cognitive performance : Findings from morphometry and quantitative susceptibility mapping of iron
Sammanfattning : Brain aging is a heterogeneous phenomenon, and this thesis illustrates how the course of aging can vary within individuals over time and between individuals as a function of age, sex, and genetic variability. We used two contrasts from magnetic resonance imaging (MRI), namely spin-lattice T1-weighted imaging, and quantitative susceptibility mapping (QSM) from gradient-echo images, to picture the aging brain, by means of morphometric measures and brain-iron concentrations. LÄS MER
5. Cerebral arterial pulsatility imaging using 4D flow MRI : methodological development and applications in brain aging
Sammanfattning : 4D flow magnetic resonance imaging (MRI) is increasingly recognizedas a versatile tool to assess arterial and venous hemodynamics. Cerebral arterial pulsatility is typically assessed by analyzing flow waveforms over the cardiac cycle, where flow amplitude is a function of cardiac output, central arterial stiffness, and cerebrovascular resistance and compliance. LÄS MER