Sökning: "brain activity"

Visar resultat 21 - 25 av 818 avhandlingar innehållade orden brain activity.

1. 21. Apoptosis-related mechanisms in the immature brain after hypoxia-ischemia

   Författare :Xiaoyang Wang; Göteborgs universitet; []
   Nyckelord :hypoxia-ischemia; neonatal; caspase; ERK; XIAP; EPO; asialoEPO; brain;

   Sammanfattning : Aims: To characterize the activation of caspases-3 and extracellular signal-regulated kinase (ERK) in the neonatal brain after hypoxia-ischemia (HI) injury and evaluate the neuroprotective effect of X-linked inhibitor of apoptosis (XIAP) protein, erythropoietin (EPO) and the non-erythropoietic derivative asialoEPO. Methods: Seven-day-old rats or 9-day-old mice were subjected to HI. LÄS MER

3. 22. Cognitive effects of deep brain stimulation : focus on caudal zona incerta for essential tremor and Parkinson´s disease, and on bed nucleus of stria terminalis for obsessive compulsive disorder

   Författare :Johanna Philipson; Patric Blomstedt; Marjan Jahanshahi; Marwan Hariz; Jean-Luc Houéto; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Deep brain stimulation. Neuropsychology. Cognition. Parkinson’s disease. Essential tremor. Obsessive-compulsive disorder. Caudal zona incerta. Bed nucleus of stria terminalis. Functional MRI.; Neurology; neurologi;

   Sammanfattning : Preserved cognition is an important determinant for perceived Quality of Life (QoL) and has been found to be essential in order to translate improvements in primary symptoms following Deep Brain Stimulation (DBS) into activities of daily living that drive QoL. Therefore, it is important to evaluate not only the clinical improvement, but also the cognitive impact of DBS. LÄS MER

4. 23. Neuromolecular and behavioural profile of teleosts : - effects of boldness, agonistic behaviour and reproductive status

   Författare :Arshi Mustafa; Svante Winberg; Per Erik Olsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histamine receptor 1 hrh1 ; histamine receptor 2 hrh2 ; histamine receptor 3 hrh3 ; boldness; personality; aggression; Histaminergic activity; Serotonergic activty 5-HIAA 5-HT ; Dopaminergic activty DOPAC DA ; spiegeldanio spd ; wild caught zebrafish; AB zebrafish; behaviour; brain.;

   Sammanfattning : This thesis investigates if boldness is reflected in the function of brain histaminergic system in zebrafish (Danio rerio). Moreover, behavioural differences in AB line, spiegeldanio (spd) line and wild caught strain of zebrafish have also been explored apart from the winner-loser effect in AB and spd fish. LÄS MER

5. 24. Caspase-dependent and caspase-independent neuronal injury in the developing brain

   Författare :Changlian Zhu; Göteborgs universitet; []
   Nyckelord :hypoxia ischemia; neonatal; cell death; caspase; apoptosis-inducing factor; brain; apoptosis; autophagy; nitric oxide;

   Sammanfattning : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. LÄS MER

7. 25. Aspects of pathological apoptosis in the immature brain after hypoxia-ischemia

   Författare :Ulrika Hallin; Göteborgs universitet; []
   Nyckelord :neonatal; rat; brain; hypoxia-ischemia; necrosis; apoptosis; calpain; caspase; Bcl-2; Bax; mitochondria; calcineurin.;

   Sammanfattning : The cause of mechanisms underlying perinatal brain injury is not fully known, but it results in a wide variety of neurological impairments in the affected children. When injured, neurons of the newborn brain are prone to undergo programmed cell death, apoptosis, since this genetic program is normally activated in some cells during development of the nervous system, even in the perinatal period. LÄS MER