Sökning: "bradykinin"

Visar resultat 11 - 15 av 45 avhandlingar innehållade ordet bradykinin.

  1. 11. Angiotensin converting enzyme inhibition and aspirin in congestive heart failure

    Författare :Tord Juhlin; Kardiologiska klinikens forskargrupp; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical trial; ARBs; renal function; congestive heart failure; ischaemic heart disease; NSAIDs; ACE-inhibitors; aspirin; dose dependency; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : Angiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. LÄS MER

  2. 12. Contact activation on bacterial surfaces - a virulence mechanism

    Författare :Kristin Persson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General biomedical sciences; Biomedicinska vetenskaper allmänt ; sepsis; infection; S. aureus; S. typhimurium; E. coli; curli; fibrinopeptides; fibrinogen; Coagulation; contact system;

    Sammanfattning : Life-threatening conditions from bacterial infections are a major clinical problem. During a severe infection, the host responds by a massive release of pro-inflammatory mediators together with a systemic activation of systems such as the coagulation, fibrinolytic, and complement systems. LÄS MER

  3. 13. The Role of Membrane Trafficking in G Protein-Coupled Receptor Regulation

    Författare :Johan Enquist; Drug Target Discovery; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; downregulation; recycling; resensitization; desensitization; GPCR; membrane trafficking;

    Sammanfattning : Movements of a receptor in the plasma membrane and within the cell influence receptor function and physiology. I have investigated the role of such movements, generally known as membrane trafficking, in G protein-coupled receptor regulation. LÄS MER

  4. 14. Studies on vasoactivity of fibrin(ogen) derived peptides

    Författare :Katarina Saldeen; Asrar Malik; Linköpings universitet; []
    Nyckelord :Fibrin ogen derived peptides; vasoactivity; prostacyclin; nitric oxide; angiotensin converting enzyme; MEDICINE; MEDICIN;

    Sammanfattning : Fibrin accumulation is a common fmding in many pathological conditions, such as in inflammatory processes, e.g. in the lungs in pneumonia or pulmonary insufficiency after sepsis. During lysis of the fibrin by plasmin or leukocyte elastase, peptides are released that may contribute to the pathophysiological changes. LÄS MER

  5. 15. Regulation of experimentally induced airway obstruction

    Författare :Eva G. Lindström; Jan Lötvall; Linköpings universitet; []
    Nyckelord :airway obstruction; antigen; capsaicin; epithelium; inflammatory mediators; sensory neurons; tube preparation; tachykinins; formoterol; histamine; presynaptic inhibition; in vitro; guinea pig; MEDICINE; MEDICIN;

    Sammanfattning : Asthma is one of the commonest diseases in industrialized countries. The cause and mechanisms of !he disorder are still not fully unden;tood, al!hough it is known that inflammation in !he airways plays an important role. Inflammatory mediators, e.g. LÄS MER