Sökning: "bone regeneration"

Visar resultat 21 - 25 av 97 avhandlingar innehållade orden bone regeneration.

  1. 21. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation

    Författare :Cecilia Granéli; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; Mesenchymal stromal cells; Osteogenic differentiation; Adipogenic differentiation; Bone regeneration; Inflammation; Monocytes; Infection; Bacterial membrane vesicles; Compromised bone healing; Cell surface proteins; CD-markers; Osseointegration; Regenerative medicine;

    Sammanfattning : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. LÄS MER

  3. 22. On the biological behavior of barrier membranes: implications for Guided Bone Regeneration. Clinical and Experimental studies

    Författare :Alberto Turri; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Guided Bone Regeneration; Membranes;

    Sammanfattning : There is a continuous development of bone augmentation solutions to meet the rising demand for effective dental implant rehabilitations. One of the most used techniques is Guided Bone Regeneration (GBR). LÄS MER

  4. 23. Biomaterials as carriers for bone active molecules-An approach to create off-the-shelf bone substitutes

    Författare :Deepak Raina; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; Bone tissue engineering; Bone morphogenic protein-2; Zoledronic acid ZA ; calcium sulphate; Hydroxyapatite; Gelatin;

    Sammanfattning : Bone tissue is commonly transplanted during orthopedic surgeries, primarily for the management of bone defects caused by trauma or various orthopedic conditions including, but not limited to, infections and tumours. Bone grafts are a surgeon’s choice, but their associated drawbacks are paving the way for biomaterial based bone graft substitutes. LÄS MER

  5. 24. Development and optimization of a 3D in vitro model for osteogenic biomaterial evaluation

    Författare :Luis Oliveros Anerillas; Peyman Kelk; Paul J. Kingham; Mikko Lammi; Jöns Hilborn; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; angiogenesis; biomaterial; bone marrow mesenchymal stem cells; bone regeneration; hydrogel; osteoinduction; osteogenesis; scaffold; type I collagen; 3D culture; biology; biologi; biomedical laboratory science; biomedicinsk laboratorievetenskap; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : Despite the innate regenerative capabilities of bone tissue, self-repair is impaired when an injury exceeds the critical size threshold because of trauma, congenital, or pathological conditions. Autologous transplantation is the gold standard to reconstruct large bone defects. LÄS MER

  7. 25. Biodegradable magnesium implants, immunomodulation, and tissue repair/regeneration

    Författare :Heithem Ben Amara; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipose tissue; Biodegradable implants; Bone–implant interface; Bone marrow; Inflammation; Cellular mechanotransduction; Gene expression; Immunohistochemistry; Magnesium; Neovascularization; Osseointegration; Soft tissue injuries;

    Sammanfattning : The century-old paradigm of holding fractures with a metallic implant to enable bone repair, known as osteosynthesis, is still used today without alteration. Patients are increasingly being treated with metallic implants made of magnesium (Mg) that secure osteosynthesis and are reabsorbed in situ without the surgical re-entry that requires their permanent analogs. LÄS MER