Sökning: "bone morphogenetic protein"
Visar resultat 1 - 5 av 44 avhandlingar innehållade orden bone morphogenetic protein.
Sammanfattning : Bone defects in the craniofacial area are a clinical challenge and can be the result of trauma, tumour resection or congenital malformations. The golden standard for reconstruction is autologous bone grafts, but bone may not always be readily available and donor-site morbidity might follow. LÄS MER
Sammanfattning : The aim of this thesis was to study onlay bone grafting in the adult rat to improve graft incorporation and perservation of graft size. In 167 adult isogeneic lewis rats, the size maintenance and bone formation at the graft-host interface of uni- and bicortical onlays positioned in various environments and treatments were investigated. LÄS MER
3. The Anabolic - Anti-catabolic Paradigm of Augmenting Skeletal Regeneration: A Bone Quality Perspective
Sammanfattning : Successful fracture repair is a complex series of coordinated processes leading to regeneration of new bone to bridge the fracture site, remodelling of the newly formed bone and restoration of skeletal function. Disruption of these processes occurs in approximately 10% of all fractures and leads to delayed or failed healing requiring surgical interventions, increased complication rates, prolonged rehabilitation and high morbidity. LÄS MER
Sammanfattning : Bone is a remarkable multifunctional tissue with the ability to regenerate and remodel without generating any scar tissue. However, bone loss due to injury or diseases can be a great challenge and affect the patient significantly. Autologous bone grafting is commonly used throughout the world. LÄS MER
Sammanfattning : The present work addresses poor bone/implant integration and severe bone defects. In both conditions external stimuli is required for new bone to form. LÄS MER