Sökning: "bone marrow density"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden bone marrow density.

  1. 1. Vascular density and bone marrow fibrosis in childhood acute lymphoblastic leukemia

    Författare :Ulrika Norén Nyström; Anders Bergh; Erik Forestier; Göran Roos; Henrik Schrøder; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood acute lymphoblastic leukemia; microvessel density; bone marrow fibrosis; in vitro drug resistance; minimal residual disease; outcome; Oncology; Onkologi;

    Sammanfattning : Background: In childhood acute lymphoblastic leukemia (ALL), the cure rate has now reached 80% in the western world. Even so, 15¬–20% will die from the disease or treatment-related causes, among them children who did not present any known unfavorable features at diagnosis. LÄS MER

  3. 2. Osteoprotegerin in Bone Metabolism

    Författare :Helena Brändström; Uppsala universitet; []
    Nyckelord :Medical sciences; Bone; osteoprotegerin; osteoblasts; polymorphism; cytokines; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Bone turnover, remodeling, is a constant process replacing old bone with new. This complex cellular event involves resorption by osteoclasts and formation of new bone by osteoblasts. The balance between osteoblastic and osteoclastic activity is under regulation by several endocrine and paracrine factors. LÄS MER

  4. 3. On surgical techniques to increase bone density and volume. Studies in the rat and the rabbit

    Författare :Christer Slotte; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autogeneic bone; bovine bone mineral; calvaria; cortical perforation; guided bone augmentation; maxilla; microangiography; morphometry; rabbit; rat; tibia; titanium implants; vessel topography;

    Sammanfattning : BACKGROUND. Various techniques of surgical intervention have been suggested to promote bone densityand volume; however, the predictability of such techniques is not always sufficiently supported by preclinicalevaluations.AIM. LÄS MER

  5. 4. BMP implants in bone formation. Studies in rabbits and rats

    Författare :Charlotte Jeppsson; Malmö Handkirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatologi; graft resorption.; Kirurgi; Surgery; orthopaedics; traumatology; bone formation; bone graft; hydroxyapatite; collagen; bisphosphonate; rat; rabbit; titanium chamber; BMP; TGF-ß;

    Sammanfattning : Bone morphogenic proteins, BMPs, are a group endogenous proteins that are highly conserved through evolution. The amino acid sequences of about 15 different BMPs are now known and recombinant human BMPs are commercially available. Implantation of an individual BMP protein is sufficient to induce bone formation even at a subcutaneous site. LÄS MER

  7. 5. Human Bone Marrow Microenvironment in Health and Disease

    Författare :Sandro Bräunig; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic microenvironment; Imaging; Myeloproliferative neoplasms; Spatial relationships; acute lymphoblastic leukaemia ALL ; Fibrosis; Mesenchymal stromal cell; Single cell RNA sequencing;

    Sammanfattning : Hematopoietic stem cells (HSCs) are safeguarded from various threats such as stress, injury, or radiationwithin specialized microenvironments or niches within the bone marrow. In this thesis, we investigatedvarious facets of the bone marrow (BM) microenvironment and its critical role in hematopoiesis andrelated disorders. LÄS MER