Sökning: "bone ingrowth"

Visar resultat 1 - 5 av 28 avhandlingar innehållade orden bone ingrowth.

  1. 1. Basic fibroblast growth factor for stimulation of bone formation in osteoinductive and conductive implants

    Författare :Jian-Sheng Wang; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Biofysik; Biophysics; bone ingrowth; titanium chamber; hyaluronic acid; porous hydroxyapatite; bone graft; bFGF; demineralized bone matrix; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Basic Fibroblast Growth Factor (bFGF) is one of the endogenous factors found in bone matrix. bFGF is a mitogen for many cell types, including osteoblasts and chondrocytes. It can stimulate angiogenesis and osteoblast gene expression. LÄS MER

  2. 2. Allograft bone in hip revision: the effect of locally applied pharmacological treatment

    Författare :Ola Belfrage; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allograft bone; bone transplantation; bisphosphonate; bone morphogenetic proteins; hip revision; radiostereometric analysis;

    Sammanfattning : The clinical success of primary hip replacement is paramount but the need for revisions will continue to increase due to the increasing number of operated individuals. In Sweden, the number of hip revisions in 2012 exceeded 2,300. During implant loosening, some of the bone in the femur is lost, which can make the revision more difficult. LÄS MER

  3. 3. Electron beam melting: Impact of part surface properties on metal fatigue and bone ingrowth

    Författare :Rebecca Klingvall Ek; Lars-Erik Rännar; Mikael Bäckström; Jaan Hong; Ola Harrysson; Mittuniversitetet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Additive Manufacturing AM ; Electron Beam Melting EBM ; As-built surfaces; Bone Ingrowth; Metall Fatigue; Machined Surfaces; Hirtisation; Hot Isostatic Pressing HIP ;

    Sammanfattning : AbstractThe aim of this thesis is to investigate aspects on how additive manufacturing (AM) contributes to functional bone implants with the use of the electron beam melting (EBM) technology. AM manufactures parts according to computer-aided design, and the EBM technology melts powder using an electron beam, which acts similar to a laser beam. LÄS MER

  4. 4. BMP implants in bone formation. Studies in rabbits and rats

    Författare :Charlotte Jeppsson; Malmö Handkirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatologi; graft resorption.; Kirurgi; Surgery; orthopaedics; traumatology; bone formation; bone graft; hydroxyapatite; collagen; bisphosphonate; rat; rabbit; titanium chamber; BMP; TGF-ß;

    Sammanfattning : Bone morphogenic proteins, BMPs, are a group endogenous proteins that are highly conserved through evolution. The amino acid sequences of about 15 different BMPs are now known and recombinant human BMPs are commercially available. Implantation of an individual BMP protein is sufficient to induce bone formation even at a subcutaneous site. LÄS MER

  5. 5. On surgical techniques to increase bone density and volume. Studies in the rat and the rabbit

    Författare :Christer Slotte; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; autogeneic bone; bovine bone mineral; calvaria; cortical perforation; guided bone augmentation; maxilla; microangiography; morphometry; rabbit; rat; tibia; titanium implants; vessel topography;

    Sammanfattning : BACKGROUND. Various techniques of surgical intervention have been suggested to promote bone densityand volume; however, the predictability of such techniques is not always sufficiently supported by preclinicalevaluations.AIM. LÄS MER