Sökning: "bone defects"
Visar resultat 11 - 15 av 99 avhandlingar innehållade orden bone defects.
11. Biomaterials as carriers for bone active molecules-An approach to create off-the-shelf bone substitutes
Sammanfattning : Bone tissue is commonly transplanted during orthopedic surgeries, primarily for the management of bone defects caused by trauma or various orthopedic conditions including, but not limited to, infections and tumours. Bone grafts are a surgeon’s choice, but their associated drawbacks are paving the way for biomaterial based bone graft substitutes. LÄS MER
12. Craniofacial bone tissue engineering with biomimetic constructs
Sammanfattning : The repair of bone defects and nonunions remains a significant clinical problem in orthopedic and maxillofacial reconstructive surgery. Tissue engineering offers a potential approach to overcome existing limitations related to auto- and allograft tissues. LÄS MER
13. Injectable calcium sulphate and calcium phosphate bone substitutes
Sammanfattning : Two formulations of biphasic injectable bone substitutes have been developed for the treatment of bone defects and stabilisation of fragility fractures. The first formulation consists of a calcium sulphate matrix with embedded hydroxyapatite (HA) particles to provide osteoconductivity. LÄS MER
14. Development of Novel Models for Studying Osteoclasts
Sammanfattning : This thesis focuses on developing and characterizing novel models for studying osteoclasts with an emphasis on how mutations abolishing osteoclastic acidification affect osteoclast signaling and bone remodeling, as well as how to treat patients bearing these rare mutations. Bone remodeling is under normal circumstances a tightly balanced process where resorption of bone by osteoclasts is followed by adequate amounts of bone formation by osteoblasts. LÄS MER
15. Healing Processes in Cancellous Bone
Sammanfattning : Most of what is known about the biological response during fracture healing comes from numerous animal studies with shaft fractures in the long bone. However, most patients suffer from fractures closer to the ends of the long bones, in the hip, or in the vertebrae. LÄS MER