Sökning: "blood vessel formation"

Visar resultat 1 - 5 av 106 avhandlingar innehållade orden blood vessel formation.

  1. 1. Roles of the Shb and Cbl Proteins in Signal Transduction and Blood Vessel Formation

    Författare :Lingge Lu; Michael Welsh; Lars Holgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Shb; Cbl; FGF-2; NGF; PDGF; VEGF; VEGFR-2; differentiation; blood vessel formation; PC12 cells; endothelial cells; embryoid bodies; Rap1; CrkII; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Formation of blood vessels occurs through two processes: vasculogenesis and angiogenesis, which are regulated by various growth factors such as vascular endothelial growth factor, fibroblast growth factor and platelet-derived growth factor. The present study was carried out in order to investigate the roles of the Shb and Cbl proteins in growth factor-mediated signal transduction and blood vessel formation. LÄS MER

  3. 2. Blood protein coated model biomaterials : preparation, and cell and tissue response

    Författare :Eva Jansson; Hans Elwing; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Solid biomaterials are widely used in bone and in soft tissue applications. Problems may then arise due to a prolonged inflammation in the proximity of the implant, resulting in the formation of a fibrous capsule and a low vascularisation near the interface. LÄS MER

  4. 3. On Aortic Blood Flow Simulations : Scale-Resolved Image-Based CFD

    Författare :Jonas Lantz; Matts Karlsson; Shawn Shadden; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : This thesis focuses on modeling and simulation of the blood flow in the aorta, the largest artery in the human body. It is an accepted fact that abnormal biological and mechanical interactions between the blood flow and the vessel wall are involved in the genesis and progression of cardiovascular diseases. LÄS MER

  5. 4. Formation of Composite Islet Grafts : A novel strategy to promote islet survival and revascularization

    Författare :Ulrika Johansson; Peetra Magnusson; Korsgren Olle; Bo Nilsson; Federico Bertuzzi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet of Langerhans; cytokines and cytokinereceptors expression; endothelial cells; mesenchymal stromal cells; transplantation; revascularization; Clinical immunology; Klinisk immunologi; cellforskning; cellforskning;

    Sammanfattning : The islets of Langerhans are small and delicate spheroid organs scattered in the pancreas responsible for insulin production. Transplantation of isolated islets is a beneficial therapy for patients with a severe form of type 1 diabetes. LÄS MER

  7. 5. Bioactivation and binding of polycyclic aromatic hydrocarbons in blood vessel endothelia

    Författare :Lizette Granberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Polycyclic aromatic hydrocarbon; PAH; endothelial cells; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Ecotoxicology; ekotoxikologi;

    Sammanfattning : Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental pollutants formed by incomplete combustion of organic materials such as fossil fuels and wood. Experimental and epidemiological studies indicate that PAHs may be involved in the development of cardiovascular disease. LÄS MER