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1. 1. Amyloid Fibril Formation - Dye Detection and Effects of Lipids

   Författare :David Lindberg; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atomic force microscopy; fluorescence; Alzheimer’s disease; YOYO-1; amyloid fibrils; lipids; linear dichroism; FRET; circular dichroism; kinetics; Protein aggregation; insulin; thioflavin-T;

   Sammanfattning : Amyloid fibrils are long fibrillar homopolymers of self-assembled proteins. They can be formed by essentially any polypeptide, but are of particular interest because of their occurrence in several incurable and debilitating human diseases, e.g. Alzheimer’s disease (AD). LÄS MER

3. 2. Trials of Diets for Treatment of Diabetes : A comparison of diets for treatment of type 2 diabetes, aspects on long and short term effects

   Författare :Hans Guldbrand; Fredrik Nyström; Carl Johan Östgren; Staffan Lindeberg; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dietary intervention; type 2 diabetes; low-carbohydrate diet; blood glucose; blood lipids; insulin; body mass index; quality of life; inflammation; cytokine;

   Sammanfattning : BackgroundType 2 diabetes is a common disease and the prevalence has increased in large parts of the world. In treatment of diabetes the type of diet is of great importance considering metabolic factors such as glucose level and blood lipids. LÄS MER

4. 3. Effects of surgically induced weight loss on cardiovascular risk factors. Results from the intervention study Swedish Obese Subjects

   Författare :David Sjöström; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Controlled clinical trial; Intervention study; Weight loss; Blood pressure; Hypertension; NIDDM; Lipids; Gastroplasty; Gastric bypass;

   Sammanfattning : Aims: To investigate the effects of large maintained weight losses on body composition, adipose tissue distribution and cardiovascular risk factors, i.e. systolic blood pressure, diastolic blood pressure, glucose, insulin, triglycerides, cholesterol, HDL-cholesterol and uric acid. LÄS MER

5. 4. Interaction of Triglyceride-rich Lipoproteins with Platelets and Vitamin K-dependent Coagulation Factors

   Författare :Ning Xu; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Triglycerides.; Prothrombin; Protein S; Protein C; Platelets; Phospholipids; Metabolism; Lipoproteins; Lipids; Endocytosis; Electron microscopy; Cytochemistry; Coronary heart disease; Blood coagulation factors; Arachidonic acid; Atherosclerosis; Clinical chemistry; Klinisk kemi; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : 1. During incubation of platelets with 3H-arachidonic acid (20:4, n-6) and 14C-cholesterol doubly labelled and colloidal gold labelled chylomicrons (CMs) and chylomicron remnants (CMRs) CMs were taken up more efficiently than CMRs. Addition of unlabelled CMs, VLDLs, LDLs and HDLs decreased the uptake of labelled CMs. LÄS MER

7. 5. Physical activity and myocardial infarction : Epidemiological studies on the association between various types of physical activity and the risk of myocardial infarction, including certain aspects of methodology

   Författare :Eleonor Fransson; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet Institutet för Miljömedicin; []
   Nyckelord :Physical activity; hypertension; blood lipids; plasma fibrinogen; myocardial infarction; body mass index; recall bias; Physical activity; hypertension; blood lipids; plasma fibrinogen; myocardial infarction; body mass index; recall bias;

   Sammanfattning : .... LÄS MER